{"id":11949,"date":"2023-07-06T12:28:01","date_gmt":"2023-07-06T10:28:01","guid":{"rendered":"https:\/\/new.sano.science\/?post_type=people&#038;p=11949"},"modified":"2026-07-21T16:15:46","modified_gmt":"2026-07-21T14:15:46","slug":"adam-sulek","status":"publish","type":"people","link":"https:\/\/sano.science\/people\/adam-sulek\/","title":{"rendered":"Adam Su\u0142ek"},"excerpt":{"rendered":"<p>Postdoctoral Researcher<\/p>\n","protected":false},"featured_media":18595,"template":"","people_teams":[19,114],"class_list":["post-11949","people","type-people","status-publish","has-post-thumbnail","hentry","people_teams-research","people_teams-structural-and-functional-genomics-group"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Adam Su\u0142ek - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/people\/adam-sulek\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adam Su\u0142ek\" \/>\n<meta property=\"og:description\" content=\"Postdoctoral Researcher\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sano.science\/people\/adam-sulek\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Computational Personalized Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/sano.science\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-21T14:15:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sano.science\/wp-content\/uploads\/2023\/07\/Sano-Adam-Sulek.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/\",\"name\":\"Adam Su\u0142ek - Centre for Computational Personalized Medicine\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/Sano-Adam-Sulek.png\",\"datePublished\":\"2023-07-06T10:28:01+00:00\",\"dateModified\":\"2026-07-21T14:15:46+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/#primaryimage\",\"url\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/Sano-Adam-Sulek.png\",\"contentUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/Sano-Adam-Sulek.png\",\"width\":1000,\"height\":1000,\"caption\":\"Adam Su\u0142ek Sano\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/adam-sulek\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/sano.science\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"People\",\"item\":\"https:\\\/\\\/sano.science\\\/people\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Research\",\"item\":\"https:\\\/\\\/sano.science\\\/people-teams\\\/research\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Adam Su\u0142ek\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sano.science\\\/#website\",\"url\":\"https:\\\/\\\/sano.science\\\/\",\"name\":\"Centre for Computational Personalized Medicine\",\"description\":\"Sano \u2013 Centre for Computational Medicine\",\"publisher\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sano.science\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\",\"name\":\"Sano \u2013 Centre for Computational Medicine\",\"alternateName\":\"Sano\",\"url\":\"https:\\\/\\\/sano.science\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/05\\\/logo_sano_podstawowe.png\",\"contentUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/05\\\/logo_sano_podstawowe.png\",\"width\":700,\"height\":265,\"caption\":\"Sano \u2013 Centre for Computational Medicine\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/sano.science\\\/\",\"https:\\\/\\\/x.com\\\/sanoscience\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/sanoscience\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCDZ_8TcjMWUG2ZcgKKgfpwQ\",\"https:\\\/\\\/bsky.app\\\/profile\\\/sanoscience.bsky.social\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Adam Su\u0142ek - Centre for Computational Personalized Medicine","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sano.science\/people\/adam-sulek\/","og_locale":"en_US","og_type":"article","og_title":"Adam Su\u0142ek","og_description":"Postdoctoral Researcher","og_url":"https:\/\/sano.science\/people\/adam-sulek\/","og_site_name":"Centre for Computational Personalized Medicine","article_publisher":"https:\/\/www.facebook.com\/sano.science\/","article_modified_time":"2026-07-21T14:15:46+00:00","og_image":[{"width":1000,"height":1000,"url":"https:\/\/sano.science\/wp-content\/uploads\/2023\/07\/Sano-Adam-Sulek.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@sanoscience","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sano.science\/people\/adam-sulek\/","url":"https:\/\/sano.science\/people\/adam-sulek\/","name":"Adam Su\u0142ek - Centre for Computational Personalized Medicine","isPartOf":{"@id":"https:\/\/sano.science\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sano.science\/people\/adam-sulek\/#primaryimage"},"image":{"@id":"https:\/\/sano.science\/people\/adam-sulek\/#primaryimage"},"thumbnailUrl":"https:\/\/sano.science\/wp-content\/uploads\/2023\/07\/Sano-Adam-Sulek.png","datePublished":"2023-07-06T10:28:01+00:00","dateModified":"2026-07-21T14:15:46+00:00","breadcrumb":{"@id":"https:\/\/sano.science\/people\/adam-sulek\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sano.science\/people\/adam-sulek\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sano.science\/people\/adam-sulek\/#primaryimage","url":"https:\/\/sano.science\/wp-content\/uploads\/2023\/07\/Sano-Adam-Sulek.png","contentUrl":"https:\/\/sano.science\/wp-content\/uploads\/2023\/07\/Sano-Adam-Sulek.png","width":1000,"height":1000,"caption":"Adam Su\u0142ek Sano"},{"@type":"BreadcrumbList","@id":"https:\/\/sano.science\/people\/adam-sulek\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sano.science\/"},{"@type":"ListItem","position":2,"name":"People","item":"https:\/\/sano.science\/people\/"},{"@type":"ListItem","position":3,"name":"Research","item":"https:\/\/sano.science\/people-teams\/research\/"},{"@type":"ListItem","position":4,"name":"Adam Su\u0142ek"}]},{"@type":"WebSite","@id":"https:\/\/sano.science\/#website","url":"https:\/\/sano.science\/","name":"Centre for Computational Personalized Medicine","description":"Sano \u2013 Centre for Computational Medicine","publisher":{"@id":"https:\/\/sano.science\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sano.science\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/sano.science\/#organization","name":"Sano \u2013 Centre for Computational Medicine","alternateName":"Sano","url":"https:\/\/sano.science\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sano.science\/#\/schema\/logo\/image\/","url":"https:\/\/sano.science\/wp-content\/uploads\/2024\/05\/logo_sano_podstawowe.png","contentUrl":"https:\/\/sano.science\/wp-content\/uploads\/2024\/05\/logo_sano_podstawowe.png","width":700,"height":265,"caption":"Sano \u2013 Centre for Computational Medicine"},"image":{"@id":"https:\/\/sano.science\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/sano.science\/","https:\/\/x.com\/sanoscience","https:\/\/www.linkedin.com\/company\/sanoscience\/","https:\/\/www.youtube.com\/channel\/UCDZ_8TcjMWUG2ZcgKKgfpwQ","https:\/\/bsky.app\/profile\/sanoscience.bsky.social"]}]}},"acf":[],"meta_data":{"description":"<p>Adam Su\u0142ek earned his Ph.D. in Chemistry from the Jagiellonian University in 2022. His interdisciplinary research was conducted in collaboration with the Lukasiewicz Research Network &#8211; Krak\u00f3w Institute of Technology and the Faculty of Mathematics and Computer Science at the Jagiellonian University. Adam&#8217;s research interests include molecular processes in tumor proliferation, computer-aided drug design, and structural biology.<\/p>\n<p>Currently, he is working on a project that examines cell cycle dysregulation, specifically involving BRCA and CDK, which leads to uncontrolled cell proliferation. Another of his projects focuses on understanding protein thermostability and exploring the use of Protein Language Models in this field.<\/p>\n","email":"","social_media":false,"tabs":false,"quote":"","position_with_team":{"text_before_link":"Postdoctoral Researcher in","link_text":"Structural and Functional Genomics Group","text_after_link":"","link":"https:\/\/sano.science\/research-teams\/structural-and-functional-genomics\/"},"publications":[{"ID":32176,"post_author":"8","post_date":"2026-07-21 16:15:23","post_date_gmt":"2026-07-21 14:15:23","post_content":"<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-XIhDT7\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">Interpreting machine learning models trained on molecular data remains challenging, particularly at the level of individual atoms. Although many attribution methods can indicate which atoms influence a prediction, the field still lacks standardized benchmarks for determining whether these explanations are chemically and structurally meaningful.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-w7fPSA\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">To address this gap, this work introduces a controlled benchmark based on rule-derived pharmacophore annotations. Predefined geometric constraints describe the spatial arrangement of functional features within a molecule and provide reference atom sets against which model explanations can be evaluated.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-pY3VG2\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">The benchmark is accompanied by PharmacoScore, a metric that quantifies how closely atom-level attributions align with these pharmacophore-derived references. The framework was used to compare explanation methods across several model families, ranging from fragment-based approaches to distance-aware transformers that explicitly encode interatomic geometry.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-IljwbN\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">Distance-aware transformers consistently achieved higher PharmacoScore values, indicating that the atoms emphasized by their explanations more closely reflected the expected spatial relationships. Together, the benchmark and PharmacoScore provide a unified framework for systematically evaluating and comparing atom-level explainability methods in molecular machine learning.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-2gqUdL\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-gJa0es\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Autors<\/strong>: Adam&nbsp;Su\u0142ek,&nbsp;Jakub&nbsp;Klimczak,&nbsp;Jakub&nbsp;Jo\u0144czyk,&nbsp;Tomasz&nbsp;Kosciolek,&nbsp;Tomasz&nbsp;Danel,&nbsp;Barbara&nbsp;Pucelik<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-RtIONs\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/button {\"id\":\"block_6a5f7e6dca8e9\",\"name\":\"acf\/button\",\"data\":{\"title\":\"Read the article\",\"_title\":\"field_61d40397c2f0a\",\"button_type\":\"link\",\"_button_type\":\"field_63bbde3b8f0d0\",\"url\":\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S187775032600164X\",\"_url\":\"field_61d4039bc2f0b\",\"button_style\":\"primary\",\"_button_style\":\"field_63872d045d0f0\",\"target\":\"_self\",\"_target\":\"field_63872c705d0ef\",\"button_extra_classes\":\"\",\"_button_extra_classes\":\"field_642beab6a97de\"},\"align\":\"\",\"mode\":\"edit\"} \/-->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-RtIONs\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:image {\"id\":32193,\"sizeSlug\":\"large\",\"linkDestination\":\"none\",\"epAnimationGeneratedClass\":\"edplus_anim-eHjexA\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2026\/07\/FIRST-TEAM-FENG-FNP-Foundation-for-Polish-Science-1024x88.png\" alt=\"\" class=\"wp-image-32193\"\/><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-RtIONs\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-BZNiNt\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">This publication is one of the outcomes of the FIRST TEAM FENG project\u00a0<a href=\"https:\/\/www.linkedin.com\/company\/foundation-for-polish-science\/\" target=\"_blank\" rel=\"noreferrer noopener\">FNP Foundation for Polish Science<\/a>, under which\u00a0<a href=\"https:\/\/www.linkedin.com\/company\/lukasiewicz-krakow-institute-of-technology\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0141ukasiewicz \u2013 Krakow Institute of Technology<\/a>\u00a0is developing\u00a0new approaches\u00a0to the identification and evaluation of therapeutic candidates in hormone-dependent breast cancer.\u00a0<\/p>\n<!-- \/wp:paragraph -->","post_title":"Benchmarking\u00a0atom-level\u00a0explainability\u00a0against\u00a0pharmacophore-computed\u00a0labels\u00a0in\u00a0molecular\u00a0machine\u00a0learning","post_excerpt":"In: Journal of Computational Science, 2026","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"benchmarking-atom-level-explainability-against-pharmacophore-computed-labels-in-molecular-machine-learning","to_ping":"","pinged":"","post_modified":"2026-07-22 11:36:50","post_modified_gmt":"2026-07-22 09:36:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/sano.science\/?post_type=research&#038;p=32176","menu_order":0,"post_type":"research","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":20689,"post_author":"8","post_date":"2025-01-10 12:56:32","post_date_gmt":"2025-01-10 11:56:32","post_content":"<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-XgRZTp\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:heading {\"epAnimationGeneratedClass\":\"edplus_anim-sCnvNo\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-barbara-pucelik-agata-barzowska-adam-sulek-mateusz-werlos-janusz-m-dabrowski\">Barbara Pucelik, Agata Barzowska, Adam Su\u0142ek, Mateusz Wer\u0142os, Janusz M. D\u0105browski<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-XgRZTp\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-O8zz1E\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">Antibiotic resistance has become a critical global health issue, recognized within the One Health framework. Photodynamic inactivation of microorganisms (PDI) offers a promising non-invasive alternative, effective across a broad spectrum with minimal resistance risk. This study presents the synthesis, photophysical properties, and antimicrobial effects of a palladium(II)-porphyrin derivative (PdF2POH) along with its zinc(II) and free-base variants (ZnF2POH, F2POH). PdF2POH demonstrated exceptional reactive oxygen species (ROS) generation, including singlet oxygen (\u03a6\u25b3 = 0.93) and oxygen-centered radicals, confirmed through luminescence and fluorescent probe assays. All compounds exhibited strong activity against Gram-positive bacteria, with PdF2POH achieving a 6-log reduction in <em>S. aureus<\/em> viability, including biofilm disruption. PdF2POH-mediated PDI showed selectivity for bacterial over mammalian cells, particularly under lower blue light doses (up to 5 J\/cm\u00b2). Its superior efficacy over ZnF2POH and F2POH is attributed to higher ROS production through both photochemical pathways. Furthermore, PdF2POH effectively eliminated bacteria in <em>S. aureus<\/em>-infected human keratinocytes while preserving cell viability. These findings highlight Pd(II)-porphyrin as a promising photosensitizer for combating bacterial infections, supporting further exploration in advanced infection models.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-XgRZTp\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-YQZSzK\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>DOI<\/strong>: doi.org\/10.1007\/s43630-024-00538-1<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-8JFSti\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Keywords<\/strong>:\u00a0Antibiotic resistancePhotodynamic inactivation (PDI)PhotosensitizerPalladium(II)-porphyrin (PdF2POH)Reactive oxygen species (ROS)Singlet oxygenGram-positive bacteria<em>Staphylococcus aureus<\/em>Biofilm disruptionZinc(II)-porphyrin (ZnF2POH)Human keratinocytesBacterial infection therapyOne Health framework<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-XgRZTp\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/button {\"id\":\"block_67810ab796e63\",\"name\":\"acf\/button\",\"data\":{\"title\":\"READ HERE\",\"_title\":\"field_61d40397c2f0a\",\"button_type\":\"link\",\"_button_type\":\"field_63bbde3b8f0d0\",\"url\":\"https:\/\/link.springer.com\/article\/10.1007\/s43630-024-00538-1\",\"_url\":\"field_61d4039bc2f0b\",\"button_style\":\"primary\",\"_button_style\":\"field_63872d045d0f0\",\"target\":\"_self\",\"_target\":\"field_63872c705d0ef\",\"button_extra_classes\":\"\",\"_button_extra_classes\":\"field_642beab6a97de\"},\"align\":\"\",\"mode\":\"edit\"} \/-->","post_title":"Refining antimicrobial photodynamic therapy: effect of charge distribution and central metal ion in fluorinated porphyrins on effective control of planktonic and biofilm bacterial forms","post_excerpt":"Journal paper in: link.springer.com, 2024","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"refining-antimicrobial-photodynamic-therapy-effect-of-charge-distribution-and-central-metal-ion-in-fluorinated-porphyrins-on-effective-control-of-planktonic-and-biofilm-bacterial-forms","to_ping":"","pinged":"","post_modified":"2025-01-10 13:04:42","post_modified_gmt":"2025-01-10 12:04:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/sano.science\/?post_type=research&#038;p=20689","menu_order":0,"post_type":"research","post_mime_type":"","comment_count":"0","filter":"raw"}]},"_links":{"self":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people\/11949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people"}],"about":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/types\/people"}],"version-history":[{"count":18,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people\/11949\/revisions"}],"predecessor-version":[{"id":32186,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people\/11949\/revisions\/32186"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media\/18595"}],"wp:attachment":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media?parent=11949"}],"wp:term":[{"taxonomy":"people_teams","embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people_teams?post=11949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}