{"id":15459,"date":"2024-02-23T13:49:44","date_gmt":"2024-02-23T12:49:44","guid":{"rendered":"https:\/\/sano.science\/?post_type=people&#038;p=15459"},"modified":"2025-04-08T18:09:19","modified_gmt":"2025-04-08T16:09:19","slug":"lukasz-szydlowski","status":"publish","type":"people","link":"https:\/\/sano.science\/people\/lukasz-szydlowski\/","title":{"rendered":"\u0141ukasz Szyd\u0142owski"},"excerpt":{"rendered":"<p>Scientific Programmer in Structural and Functional Genomics Group<\/p>\n","protected":false},"featured_media":15460,"template":"","people_teams":[24],"class_list":["post-15459","people","type-people","status-publish","has-post-thumbnail","hentry","people_teams-alumni"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>\u0141ukasz Szyd\u0142owski - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/people\/lukasz-szydlowski\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0141ukasz Szyd\u0142owski\" \/>\n<meta property=\"og:description\" content=\"Scientific Programmer in Structural and Functional Genomics Group\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sano.science\/people\/lukasz-szydlowski\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Computational Personalized Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/sano.science\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-08T16:09:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sano.science\/wp-content\/uploads\/2024\/02\/lukasz_szydlowski.png\" \/>\n\t<meta property=\"og:image:width\" content=\"350\" \/>\n\t<meta property=\"og:image:height\" content=\"350\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sano.science\\\/people\\\/lukasz-szydlowski\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/people\\\/lukasz-szydlowski\\\/\",\"name\":\"\u0141ukasz Szyd\u0142owski - 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Then, he worked at Wageningen University (Netherlands) and Okinawa Institute of Science and Technology (Japan). He is experienced in clean power generation with simultaneous waste treatment using microbial fuel cell (MFC) technology. He was involved in designing and building reactors for bioelectrochemical studies, comparative genomics and transcriptomics of electrogenic consortia<\/span>. He was also mining microbiomes for the new species,<span lang=\"EN-US\"> as well as genetic engineering isolated strains using CRISPR. He has a strong interest in studying <\/span>metabolic interactions within microbiomes.<\/p>\n<\/div>\n<p><a href=\"https:\/\/radiogdansk.pl\/audycje\/pomyslowy-wlodzimierz\/2024\/10\/10\/gdynianin-planuje-ogrody-dla-marsjanskich-i-ksiezycowych-osadnikow\/\">\u00a0&#8220;Gdynianin planuje ogrody dla marsja\u0144skich i ksi\u0119\u017cycowych osadnik\u00f3w&#8221;<\/a><\/p>\n<p><iframe loading=\"lazy\" title=\"Astrobiologia, czyli co mo\u017ce \u017cy\u0107 w kosmosie i dlaczego to badamy? \u0141ukasz Szyd\u0142owski\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/DOjz-Sjj6Ng?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n","email":"","position_with_team":{"text_before_link":"Scientific Programmer in","link_text":"Structural and Functional Genomics Group","text_after_link":"","link":"https:\/\/sano.science\/research-teams\/structural-and-functional-genomics-group\/"},"social_media":[{"icon":{"ID":11990,"id":11990,"title":"research gate","filename":"research-gate.svg","filesize":14281,"url":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","link":"https:\/\/sano.science\/people\/maciej-malawski\/research-gate\/","alt":"","author":"5","description":"","caption":"","name":"research-gate","status":"inherit","uploaded_to":531,"date":"2023-07-06 11:18:50","modified":"2023-07-06 11:18:50","menu_order":0,"mime_type":"image\/svg+xml","type":"image","subtype":"svg+xml","icon":"https:\/\/sano.science\/wp-includes\/images\/media\/default.png","width":1,"height":1,"sizes":{"thumbnail":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","medium-width":300,"medium-height":300,"medium_large":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","medium_large-width":768,"medium_large-height":1,"large":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","large-width":1024,"large-height":1024,"1536x1536":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","1536x1536-width":1,"1536x1536-height":1,"2048x2048":"https:\/\/sano.science\/wp-content\/uploads\/2023\/05\/research-gate.svg","2048x2048-width":1,"2048x2048-height":1}},"link":"https:\/\/www.researchgate.net\/profile\/Lukasz_Szydlowski3","name":"Research Gate"}],"tabs":false,"quote":"","publications":[{"ID":19114,"post_author":"8","post_date":"2024-10-04 15:58:27","post_date_gmt":"2024-10-04 13:58:27","post_content":"<!-- wp:heading {\"epAnimationGeneratedClass\":\"edplus_anim-DgozF9\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-lukasz-m-szydlowski-nbsp-alper-a-bulbul-nbsp-anna-c-simpson-nbsp-deniz-e-kaya-nbsp-nitin-k-singh-nbsp-ugur-o-sezerman-nbsp-pawel-p-labaj-nbsp-tomasz-kosciolek-nbsp-kasthuri-venkateswaran-nbsp\">Lukasz M. Szydlowski,&nbsp;Alper A. Bulbul,&nbsp;Anna C. Simpson,&nbsp;Deniz E. Kaya,&nbsp;Nitin K. Singh,&nbsp;Ugur O. Sezerman,&nbsp;Pawe\u0142 P. \u0141abaj,&nbsp;Tomasz Kosciolek,&nbsp;Kasthuri Venkateswaran&nbsp;<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-olQC3k\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-B8vIuB\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">In our study, we used a deep learning-based tool, deepFRI, to analyze the genomes of five newly discovered Gram-positive bacterial species from the ISS, four of which are non-spore-forming and one spore-forming. This allowed for precise annotation of nearly all protein-coding genes. Comparative genomic analysis revealed common traits across all studied species, as well as unique genetic features specific to ISS microorganisms. Proteome analysis reflected these patterns, indicating adaptations to life in space, such as managing hypoosmotic stress related to microgravity, enhanced DNA repair activity to counteract increased radiation exposure, and the presence of mobile genetic elements that improve metabolism. Additionally, our findings suggest the evolution of genetic traits that may possess pathogenic capabilities, such as small molecule and peptide synthesis and ATP-dependent transporters, which could explain previous reports of increased antibiotic resistance and pathogenicity in microbes exposed to space conditions. These results suggest that the ISS microorganisms we studied have adapted to life in space, which is significant for future space missions, both in terms of bioproduction and potential therapeutic targets.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-olQC3k\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-2EctuW\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Authors<\/strong>: <a href=\"https:\/\/sano.science\/people\/lukasz-szydlowski\/\">Lukasz M. Szydlowski<\/a>,&nbsp;Alper A. Bulbul,&nbsp;Anna C. Simpson,&nbsp;Deniz E. Kaya,&nbsp;Nitin K. Singh,&nbsp;Ugur O. Sezerman,&nbsp;Pawe\u0142 P. \u0141abaj,&nbsp;<a href=\"https:\/\/sano.science\/people\/tomasz-kosciolek\/\">Tomasz Kosciolek<\/a>&nbsp;&amp;&nbsp;Kasthuri Venkateswaran&nbsp;<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-DDc0wF\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>DOI:<\/strong> https:\/\/doi.org\/10.1186\/s40168-024-01916-8<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-vUaWby\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Link to article<\/strong>: https:\/\/microbiomejournal.biomedcentral.com\/articles\/10.1186\/s40168-024-01916-8<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-lJDuvK\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Keywords<\/strong>: functional annotation, international space station, extremophiles<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-olQC3k\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/button {\"id\":\"block_6780f5dda81cc\",\"name\":\"acf\/button\",\"data\":{\"title\":\"READ HERE\",\"_title\":\"field_61d40397c2f0a\",\"button_type\":\"link\",\"_button_type\":\"field_63bbde3b8f0d0\",\"url\":\"https:\/\/microbiomejournal.biomedcentral.com\/articles\/10.1186\/s40168-024-01916-8\",\"_url\":\"field_61d4039bc2f0b\",\"button_style\":\"primary\",\"_button_style\":\"field_63872d045d0f0\",\"target\":\"_self\",\"_target\":\"field_63872c705d0ef\",\"button_extra_classes\":\"\",\"_button_extra_classes\":\"field_642beab6a97de\"},\"align\":\"\",\"mode\":\"edit\"} \/-->\n\n<!-- wp:spacer {\"height\":\"30px\",\"epAnimationGeneratedClass\":\"edplus_anim-olQC3k\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:video {\"id\":19104,\"epAnimationGeneratedClass\":\"edplus_anim-SmK5nk\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<figure class=\"wp-block-video eplus-wrapper\"><video controls src=\"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/adaptation_of_bacterial_species_from_the_international_space_station_to_life_in_space-720p.mp4\"><\/video><\/figure>\n<!-- \/wp:video -->","post_title":"Adaptation to space conditions of novel bacterial species isolated from the International Space Station revealed by functional gene annotations and comparative genome analysis","post_excerpt":"Journal paper in: microbiomejournal.biomedcentral.com, 2024","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"adaptation-to-space-conditions-of-novel-bacterial-species-isolated-from-the-international-space-station-revealed-by-functional-gene-annotations-and-comparative-genome-analysis","to_ping":"","pinged":"","post_modified":"2025-01-10 13:45:10","post_modified_gmt":"2025-01-10 12:45:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/sano.science\/?post_type=research&#038;p=19114","menu_order":0,"post_type":"research","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":20647,"post_author":"8","post_date":"2025-01-10 11:17:24","post_date_gmt":"2025-01-10 10:17:24","post_content":"<!-- wp:heading {\"epAnimationGeneratedClass\":\"edplus_anim-qKj7lS\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-pawel-szczerbiak-lukasz-m-szydlowski-witold-wydmanski-p-douglas-renfrew-julia-koehler-leman-tomasz-kosciolek\">Pawe\u0142 Szczerbiak, Lukasz M. Szydlowski, Witold Wydma\u0144ski, P. Douglas Renfrew, Julia Koehler Leman, Tomasz Kosciolek<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-BU3oJP\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-ydGv10\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">Advances in protein structure prediction have resulted in a remarkable rise in high-quality 3D models, emphasizing the need for effective computational methods to handle and explore this structural data. Our study explores structural clusters derived from the AlphaFold Protein Structure Database (AFDB), a high-quality subset of ESMAtlas, and the Microbiome Immunity Project (MIP). We generate a unified low-dimensional representation of the protein structure space, revealing that while each database occupies distinct regions, they share significant overlap in functional profiles. Key biological functions cluster within specific regions, indicating a common functional landscape across diverse datasets. To support data exploration, we developed an open-access web server. These findings provide a foundation for further research into protein sequence-structure-function relationships, including taxonomic classification, environmental influences, and functional specificity.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-BU3oJP\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-b6JXoH\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>DOI<\/strong>: https:\/\/doi.org\/10.1101\/2024.08.14.607935<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-nv0xgb\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Keywords<\/strong>: protein structure prediction3D modelsAlphaFold Protein Structure Database (AFDB)ESMAtlasMicrobiome Immunity Project (MIP)structural clusterslow-dimensional representationfunctional profilesbiological functionsopen-access web serverprotein sequence-structure-function relationships<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-BU3oJP\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/button {\"id\":\"block_6780f1729ec59\",\"name\":\"acf\/button\",\"data\":{\"title\":\"READ HERE\",\"_title\":\"field_61d40397c2f0a\",\"button_type\":\"link\",\"_button_type\":\"field_63bbde3b8f0d0\",\"url\":\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.08.14.607935v2\",\"_url\":\"field_61d4039bc2f0b\",\"button_style\":\"primary\",\"_button_style\":\"field_63872d045d0f0\",\"target\":\"_self\",\"_target\":\"field_63872c705d0ef\",\"button_extra_classes\":\"\",\"_button_extra_classes\":\"field_642beab6a97de\"},\"align\":\"\",\"mode\":\"edit\"} \/-->","post_title":"Large protein databases reveal structural complementarity and functional locality","post_excerpt":"Journal paper in: www.biorxiv.org\/content, 2024","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"large-protein-databases-reveal-structural-complementarity-and-functional-locality","to_ping":"","pinged":"","post_modified":"2025-01-10 13:44:35","post_modified_gmt":"2025-01-10 12:44:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/sano.science\/?post_type=research&#038;p=20647","menu_order":0,"post_type":"research","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":20702,"post_author":"8","post_date":"2025-01-10 13:11:05","post_date_gmt":"2025-01-10 12:11:05","post_content":"<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-sMidxN\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:heading {\"epAnimationGeneratedClass\":\"edplus_anim-WNUP7L\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-stefanie-duller-simone-vrbancic-lukasz-szydlowski-alexander-mahnert-marcus-blohs-michael-predl-christina-kumpitsch-verena-zrim-christoph-hogenauer-tomasz-kosciolek-ruth-a-schmitz-anna-eberhard-melanie-dragovan-laura-schmidberger-tamara-zurabischvili-viktoria-weinberger-adrian-mathias-moser-dagmar-kolb-dominique-pernitsch-rokhsareh-mohammadzadeh-torben-kuhnast-thomas-rattei-christine-moissl-eichinger\">Stefanie Duller,\u00a0Simone Vrbancic,\u00a0 \u0141ukasz Szyd\u0142owski,\u00a0 Alexander Mahnert,\u00a0 Marcus Blohs,\u00a0 Michael Predl,\u00a0Christina Kumpitsch,\u00a0 Verena Zrim,\u00a0Christoph H\u00f6genauer,\u00a0Tomasz Kosciolek,\u00a0 Ruth A. Schmitz,\u00a0Anna Eberhard,\u00a0Melanie Dragovan,\u00a0Laura Schmidberger,\u00a0Tamara Zurabischvili, Viktoria Weinberger,\u00a0Adrian Mathias Moser,\u00a0Dagmar Kolb,\u00a0Dominique Pernitsch,\u00a0Rokhsareh Mohammadzadeh,\u00a0 Torben K\u00fchnast, Thomas Rattei,Christine Moissl-Eichinger\u00a0<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-sMidxN\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-YKq6IE\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\">Archaea play a crucial role in the human microbiome, yet their study in the gastrointestinal tract (GIT) remains limited due to a lack of cultured strains. This study introduces a method for enriching and isolating methanogenic archaea from human fecal samples using methane breath testing, in silico metabolic modeling, media optimization, FACS, dilution series, and Nanopore sequencing. The approach also involves analyzing co-cultured bacteria, comparative genomics, functional analysis, and protein structure-based function prediction. Stable archaeal cultures were established from 14 of 16 fecal samples, yielding nine previously uncultivated strains, eight of which were absent from a recent archaeome genome catalog. Genomic comparisons of <em>Methanobrevibacter smithii<\/em> and <em>Candidatus Methanobrevibacter intestini<\/em> revealed traits potentially linked to gastrointestinal diseases. This work expands available archaeal strains for GIT research and provides new insights into the adaptability of <em>Candidatus Methanobrevibacter intestini<\/em> in the human microbiome.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-sMidxN\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-TTVH8d\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>DOI<\/strong>: 10.1038\/s41467-024-52037-7<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph {\"epAnimationGeneratedClass\":\"edplus_anim-UXPFFS\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<p class=\" eplus-wrapper\"><strong>Keywords<\/strong>: ArchaeaGastrointestinal tract (GIT)Human microbiomeMethanogenic archaeaMethane breath testingFACSNanopore sequencing<em>Methanobrevibacter smithii<\/em><em>Candidatus Methanobrevibacter intestini<\/em>Comparative genomicsFunctional analysisMicrobiome adaptability<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:spacer {\"height\":\"40px\",\"epAnimationGeneratedClass\":\"edplus_anim-sMidxN\",\"epGeneratedClass\":\"eplus-wrapper\"} -->\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n<!-- \/wp:spacer -->\n\n<!-- wp:acf\/button {\"id\":\"block_67810de554642\",\"name\":\"acf\/button\",\"data\":{\"title\":\"READ HERE\",\"_title\":\"field_61d40397c2f0a\",\"button_type\":\"link\",\"_button_type\":\"field_63bbde3b8f0d0\",\"url\":\"https:\/\/www.nature.com\/articles\/s41467-024-52037-7\",\"_url\":\"field_61d4039bc2f0b\",\"button_style\":\"primary\",\"_button_style\":\"field_63872d045d0f0\",\"target\":\"_self\",\"_target\":\"field_63872c705d0ef\",\"button_extra_classes\":\"\",\"_button_extra_classes\":\"field_642beab6a97de\"},\"align\":\"\",\"mode\":\"edit\"} \/-->","post_title":"Targeted isolation of Methanobrevibacter strains from fecal samples expands the cultivated human archaeome","post_excerpt":"Journal paper in: www.nature.com, 2024","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"targeted-isolation-of-methanobrevibacter-strains-from-fecal-samples-expands-the-cultivated-human-archaeome","to_ping":"","pinged":"","post_modified":"2025-02-03 15:35:48","post_modified_gmt":"2025-02-03 14:35:48","post_content_filtered":"","post_parent":0,"guid":"https:\/\/sano.science\/?post_type=research&#038;p=20702","menu_order":0,"post_type":"research","post_mime_type":"","comment_count":"0","filter":"raw"}]},"_links":{"self":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people\/15459","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people"}],"about":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/types\/people"}],"version-history":[{"count":7,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people\/15459\/revisions"}],"predecessor-version":[{"id":22774,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people\/15459\/revisions\/22774"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media\/15460"}],"wp:attachment":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media?parent=15459"}],"wp:term":[{"taxonomy":"people_teams","embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/people_teams?post=15459"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}