{"id":25499,"date":"2025-07-09T10:27:18","date_gmt":"2025-07-09T08:27:18","guid":{"rendered":"https:\/\/sano.science\/?p=25499"},"modified":"2025-08-13T10:10:54","modified_gmt":"2025-08-13T08:10:54","slug":"sano-researchers-present-work-at-iccs-2025-in-singapore","status":"publish","type":"post","link":"https:\/\/sano.science\/sano-researchers-present-work-at-iccs-2025-in-singapore\/","title":{"rendered":"Sano Researchers Present Work at ICCS 2025 in Singapore"},"content":{"rendered":"\n

The event convened leading experts from multiple disciplines to explore the latest developments in computational approaches to complex scientific problems. The event brought together scientists working at the intersection of mathematics, computer science, and applied domains such as life sciences, physics, and engineering. ICCS has long been recognized as a premier platform for advancing interdisciplinary discussions and presenting state-of-the-art computational methods.<\/p>\n\n\n\n

The theme of this year\u2019s conference \u2013 \u201cMaking Complex Systems Tractable Through Computational Science\u201d \u2013 highlighted the growing importance of scalable algorithms, and high-performance data analytics in addressing modern scientific challenges.<\/p>\n\n\n\n

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Sano researchers contributed a diverse range of presentations and posters:<\/h2>\n\n\n\n
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Magdalena Otta<\/a>, PhD student in the Extreme-scale Data and Computing team, gave a talk titled \u201cTowards sensitivity analysis: 3D venous modelling in the lower limb,\u201d presenting computational models supporting vascular research. The work is based on a published paper that reported an analysis of a set of idealised 3D geometries of iliac vein unification to assess the importance of shape variability, inflow conditions, and viscosity on local haemodynamics – specifically on the wall shear stress metrics. A detailed steady state analysis focused on the wall shear stress distributions below three thresholds (<0.15 Pa, <0.10 Pa <0.05 [Pa]), and transient state focused on the oscillating shear index above three thresholds (>0.25, >0.35, >0.45). All the variations implemented had an effect on the size and shape of the absolute vein wall area subject to the shear metrics of choice under the assumed flow conditions. The results will serve as a basis for the interpretation of patient-specific geometries of the iliac vein unification affected by deep vein thrombosis.<\/p>\n\n\n\n

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Jakub Klimczak<\/a> delivered a presentation titled \u201cExplainable Artificial Intelligence for Bioactivity Prediction: Unveiling the Challenges with Curated CDK2\/4\/6 Breast Cancer Dataset,\u201d focusing on the transparency and interpretability of AI models in pharmacologica applications. The talk addressed key limitations of traditional explainability approaches that rely on assumptions of feature independence and additive contributions, which often fail to capture the complexity of chemical data. Jakub showcased analyses of fingerprint-based and molecular graph models, highlighting their strong predictive performance but limited actionable insights for medicinal chemists. To bridge this gap, he proposed a novel benchmark grounded in the pharmacophore concept and introduced PharmacoScore, a new metric designed to evaluate whether machine learning explanations correctly prioritize critical pharmacophore elements over irrelevant features.<\/p>\n\n\n\n

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Piotr Kica<\/a> presented a poster titled \u201cAccelerating Cloud-Based Transcriptomics: Performance Analysis and Optimization of the STAR Aligner Workflow,\u201d co-authored with Sabina Licho\u0142ai, Micha\u0142 Orzechowski, and Maciej Malawski. The work is based on a published study that proposes a scalable, cloud-native architecture for executing STAR \u2014 one of the most widely used RNA-sequence aligners \u2014 on large-scale transcriptomic datasets. The team implemented a series of optimization techniques to significantly reduce execution time and cloud computing costs. A key improvement, the early stopping mechanism, enabled a 23% reduction in total alignment time. The study also identifies optimal EC2 instance types and evaluates the use of spot instances for cost-efficient computing. The methodology was validated through medium- and large-scale experiments.<\/p>\n\n\n\n

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Wieslaw L. Nowinski<\/a>, Senior Researcher at Sano, gave a talk titled \u201cFrom the synaptome to the connectome: data bigness estimation for the human connectome at the nanoscale.\u201d Drawing on his publication, Nowinski introduced a set of wireframe and geometric models for estimating the size and data requirements of the human nanoscale connectome. His presentation highlighted six variations of the connectomic model and 36 estimation cases, demonstrating that the storage demands for fully representing the human brain\u2019s nanoscale wiring\u2014from synapses to entire circuits\u2014exceed even the capacities of today\u2019s most advanced supercomputers. This pioneering work marks the first attempt to provide precise estimations of the data needed to model the entire human connectome at nanoscale resolution.<\/p>\n\n\n\n

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Pawe\u0142 Szczerbiak<\/a>, postdoctoral researcher in the Structural and Functional Genomics Group, and Maciej Malawski<\/a>, research team leader of Extreme-scale Data and Computing, also represented Sano at the event. They actively engaged in sessions on computational genomics, cloud architecture, quantum machine learning, and scalable infrastructures. Notably, the event facilitated valuable networking opportunities, laying the groundwork for potential future collaborations.<\/p>\n\n\n\n

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Participation in ICCS 2025 underscores Sano\u2019s ongoing commitment to advancing computational tools for precision medicine and contributing to the global scientific community working at the forefront of computational science and high-performance biomedical data processing.<\/p>\n<\/div>\n<\/div>\n\n\n

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While in Singapore for ICCS 2025, the Sano team also took the opportunity to visit the NUS Mind Science Centre<\/a> (NMSC). This pioneering institution, affiliated with the National University of Singapore, promotes an interdisciplinary approach to understanding mental resilience, ageing, and psychological well-being. Its research and outreach programmes bridge neuroscience, behavioural science, and preventive healthcare, with a strong emphasis on real-world applications in education, eldercare, and youth mental health. By combining academic rigor with community engagement, NMSC stands at the forefront of efforts to translate brain science into impactful, evidence-based interventions across the human lifespan.<\/p>\n","protected":false},"excerpt":"Advancing interdisciplinary science through computational innovation, Sano \u2013 Centre for Computational Medicine joined researchers from around the globe at ICCS 2025 in Singapore, held from 7 to 9 July.","author":8,"featured_media":25503,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"editor_plus_post_options":"{}","editor_plus_copied_stylings":"{}","footnotes":""},"categories":[1],"tags":[],"class_list":["post-25499","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"\nSano Researchers Present Work at ICCS 2025 in Singapore - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/sano-researchers-present-work-at-iccs-2025-in-singapore\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sano Researchers Present Work at ICCS 2025 in Singapore\" \/>\n<meta property=\"og:description\" content=\"Advancing interdisciplinary science through computational innovation, Sano \u2013 Centre for Computational Medicine joined researchers from around the globe at ICCS 2025 in Singapore, held from 7 to 9 July.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sano.science\/sano-researchers-present-work-at-iccs-2025-in-singapore\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Computational Personalized Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/sano.science\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-09T08:27:18+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-08-13T08:10:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Maciej-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Sano\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:site\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sano\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sano.science\\\/sano-researchers-present-work-at-iccs-2025-in-singapore\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sano.science\\\/sano-researchers-present-work-at-iccs-2025-in-singapore\\\/\"},\"author\":{\"name\":\"Sano\",\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/person\\\/561b69b48b6a8f7904aed06df5d03c98\"},\"headline\":\"Sano Researchers Present Work at ICCS 2025 in Singapore\",\"datePublished\":\"2025-07-09T08:27:18+00:00\",\"dateModified\":\"2025-08-13T08:10:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sano.science\\\/sano-researchers-present-work-at-iccs-2025-in-singapore\\\/\"},\"wordCount\":810,\"publisher\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/sano-researchers-present-work-at-iccs-2025-in-singapore\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/ICCS_Maciej-scaled.jpg\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sano.science\\\/sano-researchers-present-work-at-iccs-2025-in-singapore\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/sano-researchers-present-work-at-iccs-2025-in-singapore\\\/\",\"name\":\"Sano Researchers Present Work at ICCS 2025 in Singapore - 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The event brought together scientists working at the intersection of mathematics, computer science, and applied domains such as life sciences, physics, and engineering. ICCS has long been recognized as a premier platform for advancing interdisciplinary discussions and presenting state-of-the-art computational methods.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">The event convened leading experts from multiple disciplines to explore the latest developments in computational approaches to complex scientific problems. The event brought together scientists working at the intersection of mathematics, computer science, and applied domains such as life sciences, physics, and engineering. ICCS has long been recognized as a premier platform for advancing interdisciplinary discussions and presenting state-of-the-art computational methods.<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-2Is4uN","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">The theme of this year\u2019s conference \u2013 \u201cMaking Complex Systems Tractable Through Computational Science\u201d \u2013 highlighted the growing importance of scalable algorithms, and high-performance data analytics in addressing modern scientific challenges.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">The theme of this year\u2019s conference \u2013 \u201cMaking Complex Systems Tractable Through Computational Science\u201d \u2013 highlighted the growing importance of scalable algorithms, and high-performance data analytics in addressing modern scientific challenges.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/heading","attrs":{"epAnimationGeneratedClass":"edplus_anim-PbPpaM","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-sano-researchers-contributed-a-diverse-range-of-presentations-and-posters\">Sano researchers contributed a diverse range of presentations and posters:<\/h2>\n","innerContent":["\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-sano-researchers-contributed-a-diverse-range-of-presentations-and-posters\">Sano researchers contributed a diverse range of presentations and posters:<\/h2>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-QwkVnw","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/magdalena-otta\/\">Magdalena Otta<\/a>, PhD student in the Extreme-scale Data and Computing team, gave a talk titled \u201cTowards sensitivity analysis: 3D venous modelling in the lower limb,\u201d presenting computational models supporting vascular research. The work is based on a published paper that reported an analysis of a set of idealised 3D geometries of iliac vein unification to assess the importance of shape variability, inflow conditions, and viscosity on local haemodynamics - specifically on the wall shear stress metrics. A detailed steady state analysis focused on the wall shear stress distributions below three thresholds (<0.15 Pa, <0.10 Pa <0.05 [Pa]), and transient state focused on the oscillating shear index above three thresholds (>0.25, >0.35, >0.45). All the variations implemented had an effect on the size and shape of the absolute vein wall area subject to the shear metrics of choice under the assumed flow conditions. The results will serve as a basis for the interpretation of patient-specific geometries of the iliac vein unification affected by deep vein thrombosis.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/magdalena-otta\/\">Magdalena Otta<\/a>, PhD student in the Extreme-scale Data and Computing team, gave a talk titled \u201cTowards sensitivity analysis: 3D venous modelling in the lower limb,\u201d presenting computational models supporting vascular research. The work is based on a published paper that reported an analysis of a set of idealised 3D geometries of iliac vein unification to assess the importance of shape variability, inflow conditions, and viscosity on local haemodynamics - specifically on the wall shear stress metrics. A detailed steady state analysis focused on the wall shear stress distributions below three thresholds (<0.15 Pa, <0.10 Pa <0.05 [Pa]), and transient state focused on the oscillating shear index above three thresholds (>0.25, >0.35, >0.45). All the variations implemented had an effect on the size and shape of the absolute vein wall area subject to the shear metrics of choice under the assumed flow conditions. The results will serve as a basis for the interpretation of patient-specific geometries of the iliac vein unification affected by deep vein thrombosis.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/gallery","attrs":{"linkTo":"none","epAnimationGeneratedClass":"edplus_anim-MbAEIw","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[{"blockName":"core\/image","attrs":{"id":25504,"sizeSlug":"large","linkDestination":"none","epAnimationGeneratedClass":"edplus_anim-tVIL29","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Piotra_Maciek-1024x826.jpg\" alt=\"\" class=\"wp-image-25504\"\/><\/figure>\n","innerContent":["\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Piotra_Maciek-1024x826.jpg\" alt=\"\" class=\"wp-image-25504\"\/><\/figure>\n"]},{"blockName":"core\/image","attrs":{"id":25505,"sizeSlug":"large","linkDestination":"none","epAnimationGeneratedClass":"edplus_anim-LiMl9n","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Jakub-1024x768.jpg\" alt=\"\" class=\"wp-image-25505\"\/><\/figure>\n","innerContent":["\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Jakub-1024x768.jpg\" alt=\"\" class=\"wp-image-25505\"\/><\/figure>\n"]}],"innerHTML":"\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper\">\n\n<\/figure>\n","innerContent":["\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper\">",null,"\n\n",null,"<\/figure>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-xO4W2Y","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/jakub-klimczak\/\">Jakub Klimczak<\/a> delivered a presentation titled \u201cExplainable Artificial Intelligence for Bioactivity Prediction: Unveiling the Challenges with Curated CDK2\/4\/6 Breast Cancer Dataset,\u201d focusing on the transparency and interpretability of AI models in pharmacologica applications. The talk addressed key limitations of traditional explainability approaches that rely on assumptions of feature independence and additive contributions, which often fail to capture the complexity of chemical data. Jakub showcased analyses of fingerprint-based and molecular graph models, highlighting their strong predictive performance but limited actionable insights for medicinal chemists. To bridge this gap, he proposed a novel benchmark grounded in the pharmacophore concept and introduced PharmacoScore, a new metric designed to evaluate whether machine learning explanations correctly prioritize critical pharmacophore elements over irrelevant features.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/jakub-klimczak\/\">Jakub Klimczak<\/a> delivered a presentation titled \u201cExplainable Artificial Intelligence for Bioactivity Prediction: Unveiling the Challenges with Curated CDK2\/4\/6 Breast Cancer Dataset,\u201d focusing on the transparency and interpretability of AI models in pharmacologica applications. The talk addressed key limitations of traditional explainability approaches that rely on assumptions of feature independence and additive contributions, which often fail to capture the complexity of chemical data. Jakub showcased analyses of fingerprint-based and molecular graph models, highlighting their strong predictive performance but limited actionable insights for medicinal chemists. To bridge this gap, he proposed a novel benchmark grounded in the pharmacophore concept and introduced PharmacoScore, a new metric designed to evaluate whether machine learning explanations correctly prioritize critical pharmacophore elements over irrelevant features.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-bbBwT4","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/piotr-kica\/\">Piotr Kica<\/a> presented a poster titled \u201cAccelerating Cloud-Based Transcriptomics: Performance Analysis and Optimization of the STAR Aligner Workflow,\u201d co-authored with Sabina Licho\u0142ai, Micha\u0142 Orzechowski, and Maciej Malawski. The work is based on a published study that proposes a scalable, cloud-native architecture for executing STAR \u2014 one of the most widely used RNA-sequence aligners \u2014 on large-scale transcriptomic datasets. The team implemented a series of optimization techniques to significantly reduce execution time and cloud computing costs. A key improvement, the early stopping mechanism, enabled a 23% reduction in total alignment time. The study also identifies optimal EC2 instance types and evaluates the use of spot instances for cost-efficient computing. The methodology was validated through medium- and large-scale experiments.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/piotr-kica\/\">Piotr Kica<\/a> presented a poster titled \u201cAccelerating Cloud-Based Transcriptomics: Performance Analysis and Optimization of the STAR Aligner Workflow,\u201d co-authored with Sabina Licho\u0142ai, Micha\u0142 Orzechowski, and Maciej Malawski. The work is based on a published study that proposes a scalable, cloud-native architecture for executing STAR \u2014 one of the most widely used RNA-sequence aligners \u2014 on large-scale transcriptomic datasets. The team implemented a series of optimization techniques to significantly reduce execution time and cloud computing costs. A key improvement, the early stopping mechanism, enabled a 23% reduction in total alignment time. The study also identifies optimal EC2 instance types and evaluates the use of spot instances for cost-efficient computing. The methodology was validated through medium- and large-scale experiments.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/gallery","attrs":{"linkTo":"none","epAnimationGeneratedClass":"edplus_anim-4hVzVt","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[{"blockName":"core\/image","attrs":{"id":25506,"sizeSlug":"large","linkDestination":"none","epAnimationGeneratedClass":"edplus_anim-fAYDnB","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Wieslaw-1024x576.jpg\" alt=\"\" class=\"wp-image-25506\"\/><\/figure>\n","innerContent":["\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Wieslaw-1024x576.jpg\" alt=\"\" class=\"wp-image-25506\"\/><\/figure>\n"]},{"blockName":"core\/image","attrs":{"id":25502,"sizeSlug":"large","linkDestination":"none","epAnimationGeneratedClass":"edplus_anim-tXELi6","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Pawel-1024x768.jpg\" alt=\"\" class=\"wp-image-25502\"\/><\/figure>\n","innerContent":["\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Pawel-1024x768.jpg\" alt=\"\" class=\"wp-image-25502\"\/><\/figure>\n"]}],"innerHTML":"\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper\">\n\n<\/figure>\n","innerContent":["\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped eplus-wrapper\">",null,"\n\n",null,"<\/figure>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-LQ6tuk","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/wieslaw-nowinski\/\">Wieslaw L. Nowinski<\/a>, Senior Researcher at Sano, gave a talk titled \u201cFrom the synaptome to the connectome: data bigness estimation for the human connectome at the nanoscale.\u201d Drawing on his publication, Nowinski introduced a set of wireframe and geometric models for estimating the size and data requirements of the human nanoscale connectome. His presentation highlighted six variations of the connectomic model and 36 estimation cases, demonstrating that the storage demands for fully representing the human brain\u2019s nanoscale wiring\u2014from synapses to entire circuits\u2014exceed even the capacities of today\u2019s most advanced supercomputers. This pioneering work marks the first attempt to provide precise estimations of the data needed to model the entire human connectome at nanoscale resolution.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/wieslaw-nowinski\/\">Wieslaw L. Nowinski<\/a>, Senior Researcher at Sano, gave a talk titled \u201cFrom the synaptome to the connectome: data bigness estimation for the human connectome at the nanoscale.\u201d Drawing on his publication, Nowinski introduced a set of wireframe and geometric models for estimating the size and data requirements of the human nanoscale connectome. His presentation highlighted six variations of the connectomic model and 36 estimation cases, demonstrating that the storage demands for fully representing the human brain\u2019s nanoscale wiring\u2014from synapses to entire circuits\u2014exceed even the capacities of today\u2019s most advanced supercomputers. This pioneering work marks the first attempt to provide precise estimations of the data needed to model the entire human connectome at nanoscale resolution.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-hvJFOl","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/pawel-szczerbiak\/\">Pawe\u0142 Szczerbiak<\/a>, postdoctoral researcher in the Structural and Functional Genomics Group, and <a href=\"https:\/\/sano.science\/people\/maciej-malawski\/\">Maciej Malawski<\/a>, research team leader of Extreme-scale Data and Computing, also represented Sano at the event. They actively engaged in sessions on computational genomics, cloud architecture, quantum machine learning, and scalable infrastructures. Notably, the event facilitated valuable networking opportunities, laying the groundwork for potential future collaborations.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/people\/pawel-szczerbiak\/\">Pawe\u0142 Szczerbiak<\/a>, postdoctoral researcher in the Structural and Functional Genomics Group, and <a href=\"https:\/\/sano.science\/people\/maciej-malawski\/\">Maciej Malawski<\/a>, research team leader of Extreme-scale Data and Computing, also represented Sano at the event. They actively engaged in sessions on computational genomics, cloud architecture, quantum machine learning, and scalable infrastructures. Notably, the event facilitated valuable networking opportunities, laying the groundwork for potential future collaborations.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/columns","attrs":{"epStylingOptions":{"epCustomColumnsResponsiveEnabled":true,"epCustomColumnsReverseResponsiveEnabled":true,"epCustomColumnsSpacingResponsiveEnabled":true,"epCustomColumns":{"target":"wp-block-column","responsive":true,"hover":false,"options":[{"custom":true,"control":"ColumnToggle"},{"label":"Responsive 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Order","control":"ButtonGroup","attribute":"epCustomColumnsReverse","css":"flex-direction","customValue":"{{value}}","condition":{"relation":"AND","query":[{"field":"attributes.className","compare":"IN","value":"ep-custom-column"},[{"relation":"OR","query":[[{"relation":"AND","query":[{"field":"attributes.epCustomColumns.mobile","controlledBy":"Range","compare":"IN","value":"1"},{"field":"viewport","compare":"EQUAL","value":"mobile"}]}],[{"relation":"AND","query":[{"field":"attributes.epCustomColumns.tablet","controlledBy":"Range","compare":"IN","value":"1"},{"field":"viewport","compare":"EQUAL","value":"tablet"}]}]]}]]},"defaults":{"tablet":"column","mobile":"column"},"props":{"layout":"stacked","options":[{"label":"Default","value":"column"},{"label":"Reverse","value":"column-reverse"}]}}]},"epCustomColumnsSpacing":{"target":"","responsive":true,"hover":false,"options":[{"label":"Columns Gap","control":"Range","attribute":"epCustomColumnsSpacing","defaults":{"desktop":"32px","tablet":"32px","mobile":"32px"},"css":"gap","props":{"max":100,"min":0,"supportedUnits":["px"]},"condition":{"query":[{"field":"attributes.className","compare":"IN","value":"ep-custom-column"}]}}]},"savedStyling":"","clientId":"a2da5293-acb4-4e10-8a45-38829b00cd1d"},"epCustomColumns":{"desktop":{"value":"","important":false,"unit":"%"},"tablet":{"value":2,"important":false,"unit":""},"tabletModified":true,"mobile":{"value":1,"important":false,"unit":""},"mobileModified":true},"epCustomColumnsSpacing":{"desktop":{"value":32,"important":false,"unit":"px"},"tablet":{"value":32,"important":false,"unit":"px"},"tabletModified":true,"mobile":{"value":32,"important":false,"unit":"px"},"mobileModified":true},"epCustomColumnsReverse":{"desktop":"","tablet":"column","tabletModified":true,"mobile":"column","mobileModified":true},"epAnimationGeneratedClass":"edplus_anim-tuiQ5B","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[{"blockName":"core\/column","attrs":{"epAnimationGeneratedClass":"edplus_anim-VojHNc","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[{"blockName":"core\/image","attrs":{"id":25503,"sizeSlug":"large","linkDestination":"none","epAnimationGeneratedClass":"edplus_anim-TYE1z4","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Maciej-1024x768.jpg\" alt=\"\" class=\"wp-image-25503\"\/><\/figure>\n","innerContent":["\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Maciej-1024x768.jpg\" alt=\"\" class=\"wp-image-25503\"\/><\/figure>\n"]}],"innerHTML":"\n<div class=\"wp-block-column eplus-wrapper\"><\/div>\n","innerContent":["\n<div class=\"wp-block-column eplus-wrapper\">",null,"<\/div>\n"]},{"blockName":"core\/column","attrs":{"verticalAlignment":"center","epAnimationGeneratedClass":"edplus_anim-yH1B3J","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-q4eNAY","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">Participation in ICCS 2025 underscores Sano\u2019s ongoing commitment to advancing computational tools for precision medicine and contributing to the global scientific community working at the forefront of computational science and high-performance biomedical data processing.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">Participation in ICCS 2025 underscores Sano\u2019s ongoing commitment to advancing computational tools for precision medicine and contributing to the global scientific community working at the forefront of computational science and high-performance biomedical data processing.<\/p>\n"]}],"innerHTML":"\n<div class=\"wp-block-column is-vertically-aligned-center eplus-wrapper\"><\/div>\n","innerContent":["\n<div class=\"wp-block-column is-vertically-aligned-center eplus-wrapper\">",null,"<\/div>\n"]}],"innerHTML":"<div class=\"wp-block-columns eplus-wrapper eplus-styles-uid-ffa756\">\n\n<\/div>","innerContent":["\n<div class=\"wp-block-columns eplus-wrapper\">",null,"\n\n",null,"<\/div>\n"]},{"blockName":"core\/spacer","attrs":{"height":"30px","epAnimationGeneratedClass":"edplus_anim-QCJdPJ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-hvJFOl","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">While in Singapore for ICCS 2025, the Sano team also took the opportunity to visit the <a href=\"https:\/\/www.suss.edu.sg\/partnerships\/detail\/nus-mind-science-centre-(nmsc)\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">NUS Mind Science Centre<\/a> (NMSC). This pioneering institution, affiliated with the National University of Singapore, promotes an interdisciplinary approach to understanding mental resilience, ageing, and psychological well-being. Its research and outreach programmes bridge neuroscience, behavioural science, and preventive healthcare, with a strong emphasis on real-world applications in education, eldercare, and youth mental health. By combining academic rigor with community engagement, NMSC stands at the forefront of efforts to translate brain science into impactful, evidence-based interventions across the human lifespan.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">While in Singapore for ICCS 2025, the Sano team also took the opportunity to visit the <a href=\"https:\/\/www.suss.edu.sg\/partnerships\/detail\/nus-mind-science-centre-(nmsc)\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">NUS Mind Science Centre<\/a> (NMSC). This pioneering institution, affiliated with the National University of Singapore, promotes an interdisciplinary approach to understanding mental resilience, ageing, and psychological well-being. Its research and outreach programmes bridge neuroscience, behavioural science, and preventive healthcare, with a strong emphasis on real-world applications in education, eldercare, and youth mental health. By combining academic rigor with community engagement, NMSC stands at the forefront of efforts to translate brain science into impactful, evidence-based interventions across the human lifespan.<\/p>\n"]}],"meta_data":{"has_thumbnail_pattern":false,"share_on_social_media":{"has_social_media":false}},"featured_image":{"url":"https:\/\/sano.science\/wp-content\/uploads\/2025\/07\/ICCS_Maciej-1024x768.jpg"},"main_category":{"name":"Uncategorized"},"prev_page":{"slug":"sano-hosts-professor-alberto-cacciola-for-collaborative-discussions"},"next_page":{"slug":"advancing-explainable-ai-in-drug-discovery"},"_links":{"self":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts\/25499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/comments?post=25499"}],"version-history":[{"count":6,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts\/25499\/revisions"}],"predecessor-version":[{"id":25636,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts\/25499\/revisions\/25636"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media\/25503"}],"wp:attachment":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media?parent=25499"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/categories?post=25499"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/tags?post=25499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}