{"id":33081,"date":"2026-10-07T12:06:05","date_gmt":"2026-10-07T10:06:05","guid":{"rendered":"https:\/\/sano.science\/?p=33081"},"modified":"2026-10-28T12:09:21","modified_gmt":"2026-10-28T11:09:21","slug":"from-gut-to-brain-bacterial-amyloids-and-parkinsons","status":"publish","type":"post","link":"https:\/\/sano.science\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\/","title":{"rendered":"From gut to brain: bacterial amyloids and Parkinson’s"},"content":{"rendered":"\n

Sano researchers Alicja W. Wojciechowska<\/a>, Jakub W. Wojciechowski<\/a> and Tomasz Ko\u015bci\u00f3\u0142ek<\/a> are among the authors of a new study, \u201cAggregation in gut: on the link between neurodegeneration and bacterial functional amyloids,” published in npj Biofilms and Microbiomes (Nature Portfolio), with Kinga Zieli\u0144ska, Johannes S\u00f6ding and Ma\u0142gorzata Kotulska. Using a bioinformatics approach, the team identifies “functional amyloids” \u2014 protein aggregates that gut bacteria produce for useful purposes, such as stabilising biofilms \u2014 and examines how they might affect human health through the gut\u2013brain axis (the two-way link between the gut and the brain). They report a greater relative abundance of these bacterial amyloids in people diagnosed with Parkinson’s disease in two of three datasets, pointing to a tentative link between gut bacteria and neurodegeneration that still needs experimental validation.<\/p>\n\n\n\n

“Aggregation in gut: on the link between neurodegeneration and bacterial functional amyloids.”<\/a>
Autors: Alicja W. Wojciechowska, Jakub W. Wojciechowski, Kinga Zielinska, Johannes Soeding, Tomasz Kosciolek, Malgorzata Kotulska <\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":"New publication","author":8,"featured_media":30902,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"editor_plus_post_options":"{}","editor_plus_copied_stylings":"{}","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[116],"tags":[],"class_list":["post-33081","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new-paper-at-sano"],"yoast_head":"\nFrom gut to brain: bacterial amyloids and Parkinson's - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"description\" content=\"A study co-authored by Sano researchers in npj Biofilms and Microbiomes explores a tentative link between gut bacterial amyloids and Parkinson's disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"From gut to brain: bacterial amyloids and Parkinson's\" \/>\n<meta property=\"og:description\" content=\"A study co-authored by Sano researchers in npj Biofilms and Microbiomes explores a tentative link between gut bacterial amyloids and Parkinson's disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sano.science\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Computational Personalized Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/sano.science\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-07T10:06:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-28T11:09:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sano.science\/wp-content\/uploads\/2026\/04\/publications-Sano.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1217\" \/>\n\t<meta property=\"og:image:height\" content=\"647\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Sano\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:site\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sano\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sano.science\\\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sano.science\\\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\\\/\"},\"author\":{\"name\":\"Sano\",\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/person\\\/584b688db91327a7862fe87518e38c51\"},\"headline\":\"From gut to brain: bacterial amyloids and Parkinson’s\",\"datePublished\":\"2026-10-07T10:06:05+00:00\",\"dateModified\":\"2026-10-28T11:09:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sano.science\\\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\\\/\"},\"wordCount\":174,\"publisher\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2026\\\/04\\\/publications-Sano.jpg\",\"articleSection\":[\"New Paper at Sano\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sano.science\\\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/from-gut-to-brain-bacterial-amyloids-and-parkinsons\\\/\",\"name\":\"From gut to brain: bacterial amyloids and Parkinson's - 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Wojciechowska<\/a>, <a href=\"https:\/\/sano.science\/people\/jakub-wojciechowski\/\" data-type=\"people\" data-id=\"15540\">Jakub W. Wojciechowski<\/a> and <a href=\"https:\/\/sano.science\/people\/tomasz-kosciolek\/\" data-type=\"people\" data-id=\"12707\">Tomasz Ko\u015bci\u00f3\u0142ek<\/a> are among the authors of a new study, \u201cAggregation in gut: on the link between neurodegeneration and bacterial functional amyloids,\" published in npj Biofilms and Microbiomes (Nature Portfolio), with Kinga Zieli\u0144ska, Johannes S\u00f6ding and Ma\u0142gorzata Kotulska. Using a bioinformatics approach, the team identifies \"functional amyloids\" \u2014 protein aggregates that gut bacteria produce for useful purposes, such as stabilising biofilms \u2014 and examines how they might affect human health through the gut\u2013brain axis (the two-way link between the gut and the brain). They report a greater relative abundance of these bacterial amyloids in people diagnosed with Parkinson's disease in two of three datasets, pointing to a tentative link between gut bacteria and neurodegeneration that still needs experimental validation.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">Sano researchers <a href=\"https:\/\/sano.science\/people\/alicja-wojciechowska\/\" data-type=\"people\" data-id=\"24403\">Alicja W. Wojciechowska<\/a>, <a href=\"https:\/\/sano.science\/people\/jakub-wojciechowski\/\" data-type=\"people\" data-id=\"15540\">Jakub W. Wojciechowski<\/a> and <a href=\"https:\/\/sano.science\/people\/tomasz-kosciolek\/\" data-type=\"people\" data-id=\"12707\">Tomasz Ko\u015bci\u00f3\u0142ek<\/a> are among the authors of a new study, \u201cAggregation in gut: on the link between neurodegeneration and bacterial functional amyloids,\" published in npj Biofilms and Microbiomes (Nature Portfolio), with Kinga Zieli\u0144ska, Johannes S\u00f6ding and Ma\u0142gorzata Kotulska. Using a bioinformatics approach, the team identifies \"functional amyloids\" \u2014 protein aggregates that gut bacteria produce for useful purposes, such as stabilising biofilms \u2014 and examines how they might affect human health through the gut\u2013brain axis (the two-way link between the gut and the brain). They report a greater relative abundance of these bacterial amyloids in people diagnosed with Parkinson's disease in two of three datasets, pointing to a tentative link between gut bacteria and neurodegeneration that still needs experimental validation.<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-QyHCkZ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/www.nature.com\/articles\/s41522-026-01005-8\" target=\"_blank\" rel=\"noopener\">\"Aggregation in gut: on the link between neurodegeneration and bacterial functional amyloids.\"<\/a><br>Autors: Alicja W. Wojciechowska, Jakub W. Wojciechowski, Kinga Zielinska, Johannes Soeding, Tomasz Kosciolek, Malgorzata Kotulska <\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/www.nature.com\/articles\/s41522-026-01005-8\" target=\"_blank\" rel=\"noopener\">\"Aggregation in gut: on the link between neurodegeneration and bacterial functional amyloids.\"<\/a><br>Autors: Alicja W. Wojciechowska, Jakub W. Wojciechowski, Kinga Zielinska, Johannes Soeding, Tomasz Kosciolek, Malgorzata Kotulska <\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-GYRPkk","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><\/p>\n"]}],"meta_data":{"has_thumbnail_pattern":false,"share_on_social_media":{"has_social_media":false}},"featured_image":{"url":"https:\/\/sano.science\/wp-content\/uploads\/2026\/04\/publications-Sano-1024x544.jpg"},"main_category":{"name":"New Paper at Sano"},"prev_page":{"slug":"can-ai-learn-the-rules-of-the-human-body"},"next_page":{"slug":"from-atom-to-personalised-medicine"},"_links":{"self":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts\/33081","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/comments?post=33081"}],"version-history":[{"count":2,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts\/33081\/revisions"}],"predecessor-version":[{"id":33083,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/posts\/33081\/revisions\/33083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media\/30902"}],"wp:attachment":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media?parent=33081"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/categories?post=33081"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/tags?post=33081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}