{"id":8176,"date":"2021-12-20T09:18:00","date_gmt":"2021-12-20T08:18:00","guid":{"rendered":"https:\/\/sano.science\/?p=8176"},"modified":"2024-03-19T14:09:23","modified_gmt":"2024-03-19T13:09:23","slug":"new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients","status":"publish","type":"post","link":"https:\/\/sano.science\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\/","title":{"rendered":"New Genes linked to brain connectivity and dementia score in Alzheimer\u2019s patients"},"content":{"rendered":"\n<p class=\" eplus-wrapper\">A <strong>new study, published in Frontiers in Human Neuroscience<\/strong>, explores the connections between Alzheimer\u2019s disease and connectomics, a rapidly growing area in computational neuroscience which allows to see the <strong>brain as a network<\/strong>. By investigating the relationships between brain connectome, dementia scoring and genetics, scientists might shed new lights into local or network-level diagnostic biomarkers that give further insights for therapy and prevention.<br><br>One of the publication\u2019s authors is <strong>Alessandro Crimi<\/strong>, the<a href=\"https:\/\/sano.science\/research-teams\/computer-vision-data-science\/\" target=\"_blank\" rel=\"noreferrer noopener\"> Computer Vision<\/a> (Brain and More Lab) Team Leader.<br><br>Original paper: Elsheikh, S. S., Chimusa, E. R., Mulder, N. J., Crimi, A., &amp; Alzheimer&#8217;s Disease Neuroimaging Initiative. (2021). Relating Global and Local Connectome Changes to Dementia and Targeted Gene Expression in Alzheimer&#8217;s Disease Front. Hum. Neurosci., 17 December 2021 |\u00a0<a href=\"https:\/\/doi.org\/10.3389\/fnhum.2021.761424\">https:\/\/doi.org\/10.3389\/fnhum.2021.761424<\/a><br><br><br><\/p>\n\n\n\n<figure class=\"wp-embed-aspect-16-9 wp-has-aspect-ratio wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube eplus-wrapper\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Relating Global and Local Connectome Changes to Dementia and Targeted Gene Expression in Alzheimer&#039;s\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/bDPNtb5bFZc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n","protected":false},"excerpt":"Despite COVID-19 is still making headlines, Alzheimer\u2019s disease is one of the most common ailments in our aging society. New approaches for diagnosis and treatment are emerging, especially specific to certain brain regions. it\u2019s very relevant to understand the ties between this disease pathology, brain connections and genetics.","author":7,"featured_media":15888,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"editor_plus_post_options":"{}","editor_plus_copied_stylings":"{}","footnotes":""},"categories":[1],"tags":[],"class_list":["post-8176","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>New Genes linked to brain connectivity and dementia score in Alzheimer\u2019s patients - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Genes linked to brain connectivity and dementia score in Alzheimer\u2019s patients\" \/>\n<meta property=\"og:description\" content=\"Despite COVID-19 is still making headlines, Alzheimer\u2019s disease is one of the most common ailments in our aging society. New approaches for diagnosis and treatment are emerging, especially specific to certain brain regions. it\u2019s very relevant to understand the ties between this disease pathology, brain connections and genetics.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sano.science\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Computational Personalized Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/sano.science\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-12-20T08:18:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-19T13:09:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sano.science\/wp-content\/uploads\/2021\/12\/New-Genes.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"ict\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:site\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ict\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sano.science\\\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sano.science\\\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\\\/\"},\"author\":{\"name\":\"ict\",\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/person\\\/679dab979bad335501f6f78ea17cffc0\"},\"headline\":\"New Genes linked to brain connectivity and dementia score in Alzheimer\u2019s patients\",\"datePublished\":\"2021-12-20T08:18:00+00:00\",\"dateModified\":\"2024-03-19T13:09:23+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sano.science\\\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\\\/\"},\"wordCount\":146,\"publisher\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/New-Genes.png\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sano.science\\\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/new-genes-linked-to-brain-connectivity-and-dementia-score-in-alzheimers-patients\\\/\",\"name\":\"New Genes linked to brain connectivity and dementia score in Alzheimer\u2019s patients - 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