{"id":12821,"date":"2023-07-13T16:41:48","date_gmt":"2023-07-13T14:41:48","guid":{"rendered":"https:\/\/new.sano.science\/?post_type=seminars&#038;p=12821"},"modified":"2023-08-24T16:14:57","modified_gmt":"2023-08-24T14:14:57","slug":"selection-of-signature-genes-for-functional-analysis-and-classification-the-case-study-of-astrocytoma-2","status":"publish","type":"seminars","link":"https:\/\/sano.science\/seminars\/selection-of-signature-genes-for-functional-analysis-and-classification-the-case-study-of-astrocytoma-2\/","title":{"rendered":"97. Selection of signature genes for functional analysis and classification: the case study of astrocytoma"},"content":{"rendered":"\n<h2 class=\"wp-block-heading eplus-wrapper\">Abstract<\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">The development of high-throughput technologies has provided a strong foundation for the progress of modern systems biology. With the vast amount of biological data available, it is crucial to select those features that preserve the biological relevance of the data as well as those that can be used for therapeutic target discovery and classification purposes. To address this problem, many feature selection algorithms have been developed in recent years.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">During this seminar, I will introduce the most important topics related to the DW MRI, including the diffusion-weighted data acquisition and diffusion tensor imaging. In addition, I will discuss multicompartment models and the accuracy of their use with diffusion-relaxometry data and various optimization algorithms, as well as tractography algorithms and their application in the analysis of brain maturation and aging.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading eplus-wrapper\">About the author<\/h2>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\"><strong>Anna<\/strong>&nbsp;graduated from the Jagiellonian University in Krak\u00f3w, Poland with a master\u2019s degree in Laboratory Medicine and the AGH University of Science, Poland with an Engineering Degree in Materials Engineering.&nbsp;Anna completed her PhD studies at the Faculty of Physics, Astronomy and Computer Science of Jagiellonian University. In 2021 she defended her thesis titled: \u201cCharacterization and synthesis of drug carriers based on artificial exosomes dedicated to the treatment of microangiopathic diabetic complications\u201d. Her doctoral thesis was based on the research project she led, which was awarded by the National Science Centre Poland.<\/p>\n\n\n\n<p class=\"eplus-wrapper wp-block-paragraph\">Currently, she is a postdoctoral researcher at Sano \u2013 Centre for Computational Personalised Medicine \u2013 International Research Foundation in Krak\u00f3w in the Personal Health Data Science Group. In her research she combines the knowledge which she gained during her studies in different areas. Anna is particularly interested in personalised medicine, disease prevention, biomarker discovery and diabetes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anna Drozdz \u2013 Personal Health Data Science Team, Sano Centre for Computational Medicine, Krakow, PL<\/p>\n","protected":false},"featured_media":12822,"template":"","class_list":["post-12821","seminars","type-seminars","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>97. Selection of signature genes for functional analysis and classification: the case study of astrocytoma - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/seminars\/selection-of-signature-genes-for-functional-analysis-and-classification-the-case-study-of-astrocytoma-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"97. 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Selection of signature genes for functional analysis and classification: the case study of astrocytoma"}]},{"@type":"WebSite","@id":"https:\/\/sano.science\/#website","url":"https:\/\/sano.science\/","name":"Centre for Computational Personalized Medicine","description":"Sano \u2013 Centre for Computational Medicine","publisher":{"@id":"https:\/\/sano.science\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sano.science\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/sano.science\/#organization","name":"Sano \u2013 Centre for Computational Medicine","alternateName":"Sano","url":"https:\/\/sano.science\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sano.science\/#\/schema\/logo\/image\/","url":"https:\/\/sano.science\/wp-content\/uploads\/2024\/05\/logo_sano_podstawowe.png","contentUrl":"https:\/\/sano.science\/wp-content\/uploads\/2024\/05\/logo_sano_podstawowe.png","width":700,"height":265,"caption":"Sano \u2013 Centre for Computational Medicine"},"image":{"@id":"https:\/\/sano.science\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/sano.science\/","https:\/\/x.com\/sanoscience","https:\/\/www.linkedin.com\/company\/sanoscience\/","https:\/\/www.youtube.com\/channel\/UCDZ_8TcjMWUG2ZcgKKgfpwQ","https:\/\/bsky.app\/profile\/sanoscience.bsky.social"]}]}},"acf":[],"gutenberg_blocks":[{"blockName":"custom-styles","attrs":{"styles":""}},{"blockName":"core\/heading","attrs":{"epAnimationGeneratedClass":"edplus_anim-t3F7EW","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<h2 class=\"wp-block-heading eplus-wrapper\">Abstract<\/h2>\n","innerContent":["\n<h2 class=\"wp-block-heading eplus-wrapper\">Abstract<\/h2>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-a8mNj0","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">The development of high-throughput technologies has provided a strong foundation for the progress of modern systems biology. With the vast amount of biological data available, it is crucial to select those features that preserve the biological relevance of the data as well as those that can be used for therapeutic target discovery and classification purposes. To address this problem, many feature selection algorithms have been developed in recent years.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">The development of high-throughput technologies has provided a strong foundation for the progress of modern systems biology. With the vast amount of biological data available, it is crucial to select those features that preserve the biological relevance of the data as well as those that can be used for therapeutic target discovery and classification purposes. To address this problem, many feature selection algorithms have been developed in recent years.<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-gamAr7","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">During this seminar, I will introduce the most important topics related to the DW MRI, including the diffusion-weighted data acquisition and diffusion tensor imaging. In addition, I will discuss multicompartment models and the accuracy of their use with diffusion-relaxometry data and various optimization algorithms, as well as tractography algorithms and their application in the analysis of brain maturation and aging.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">During this seminar, I will introduce the most important topics related to the DW MRI, including the diffusion-weighted data acquisition and diffusion tensor imaging. In addition, I will discuss multicompartment models and the accuracy of their use with diffusion-relaxometry data and various optimization algorithms, as well as tractography algorithms and their application in the analysis of brain maturation and aging.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"50px","epAnimationGeneratedClass":"edplus_anim-2VBDSr","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/heading","attrs":{"epAnimationGeneratedClass":"edplus_anim-TF4r7Y","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<h2 class=\"wp-block-heading eplus-wrapper\">About the author<\/h2>\n","innerContent":["\n<h2 class=\"wp-block-heading eplus-wrapper\">About the author<\/h2>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-83NvDH","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><strong>Anna<\/strong>&nbsp;graduated from the Jagiellonian University in Krak\u00f3w, Poland with a master\u2019s degree in Laboratory Medicine and the AGH University of Science, Poland with an Engineering Degree in Materials Engineering.&nbsp;Anna completed her PhD studies at the Faculty of Physics, Astronomy and Computer Science of Jagiellonian University. In 2021 she defended her thesis titled: \u201cCharacterization and synthesis of drug carriers based on artificial exosomes dedicated to the treatment of microangiopathic diabetic complications\u201d. Her doctoral thesis was based on the research project she led, which was awarded by the National Science Centre Poland.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><strong>Anna<\/strong>&nbsp;graduated from the Jagiellonian University in Krak\u00f3w, Poland with a master\u2019s degree in Laboratory Medicine and the AGH University of Science, Poland with an Engineering Degree in Materials Engineering.&nbsp;Anna completed her PhD studies at the Faculty of Physics, Astronomy and Computer Science of Jagiellonian University. In 2021 she defended her thesis titled: \u201cCharacterization and synthesis of drug carriers based on artificial exosomes dedicated to the treatment of microangiopathic diabetic complications\u201d. Her doctoral thesis was based on the research project she led, which was awarded by the National Science Centre Poland.<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-fkScrL","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">Currently, she is a postdoctoral researcher at Sano \u2013 Centre for Computational Personalised Medicine \u2013 International Research Foundation in Krak\u00f3w in the Personal Health Data Science Group. In her research she combines the knowledge which she gained during her studies in different areas. Anna is particularly interested in personalised medicine, disease prevention, biomarker discovery and diabetes.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">Currently, she is a postdoctoral researcher at Sano \u2013 Centre for Computational Personalised Medicine \u2013 International Research Foundation in Krak\u00f3w in the Personal Health Data Science Group. In her research she combines the knowledge which she gained during her studies in different areas. 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