{"id":19296,"date":"2024-10-11T19:05:20","date_gmt":"2024-10-11T17:05:20","guid":{"rendered":"https:\/\/sano.science\/?post_type=seminars&p=19296"},"modified":"2025-02-26T19:54:03","modified_gmt":"2025-02-26T18:54:03","slug":"computational-models-to-improve-the-stratification-of-patients-with-spine-metastases","status":"publish","type":"seminars","link":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/","title":{"rendered":"147. Computational Models to Improve the Stratification of Patients with Spine Metastases"},"content":{"rendered":"\n

Abstract:<\/h2>\n\n\n\n
<\/div>\n\n\n\n

The spine is the most common anatomical site for the localization of bone metastases from different types of primary tumours (30-70% of patients with cancer, estimated to be ~2.7M in Europe). Fractures occur in 30% of metastatic spines. Currently scoring systems such as the Spine Instability Neoplastic Score (SINS) are used by clinicians to estimate the risk of fracture in these patients and decide who needs treatment, usually an invasive surgery. Nevertheless, these scores are not specific and sensitive enough. CT-based Subject Specific Finite Element (SSFE) models have been used to evaluate the effect of skeletal diseases and related treatments in the spine.<\/p>\n\n\n\n

In this seminar I will:<\/p>\n\n\n\n

-) introduce a new experimental and imaging pipeline to characterize the failure modes of vertebrae with metastatic lesions;<\/p>\n\n\n\n

-) present a pipeline to create SSFE models of vertebrae with metastatic lesions and adjacent radiographically healthy control vertebrae from CT images of patients with spine metastases;<\/p>\n\n\n\n

-) introduce the METASTRA project (https:\/\/www.metastraproject.eu\/<\/a>), which is funded by the EU and aims at developing the first decision support tool based on computational models to stratify patients with spine metastases that are at high risk of fracture.<\/p>\n\n\n\n

<\/div>\n\n\n\n

About the author:<\/h2>\n\n\n\n
<\/div>\n\n\n\n

Prof. Dall\u2019Ara (https:\/\/www.sheffield.ac.uk\/smph\/people\/clinical-medicine\/enrico-dallara<\/a>) is Professor of Musculoskeletal Biomechanics at the University of Sheffield. He is the Director of the Skelet.Al laboratories, the Research Director of the Insigneo Computational Modelling in Medicine research theme, and the President of the European Society of Biomechanics. His research focuses on better understanding the properties of musculoskeletal tissues across the space and time scales, by using imaging, experimental and computational methods. He has received funding from EPSRC, NC3Rs, BBSRC, FNRS\/FWO, and the European Commission including the recent METASTRA project. In 2024 he has been selected for an ERC consolidator award that has been funded by the EPSRC through the EU Guarantee fund with the title: Virtual Mouse and Human Twins for optimising Treatments for Osteoporosis (VMHTsOP).<\/p>\n\n\n\n

<\/div>\n\n\n\n
\"\"<\/figure>\n\n\n\n
<\/div>\n\n\n\n

regulations<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

E. Dall\u2019Ara – University of Sheffield, Insigneo Institute<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-19296","seminars","type-seminars","status-publish","hentry"],"yoast_head":"\n147. Computational Models to Improve the Stratification of Patients with Spine Metastases - Centre for Computational Personalized Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"147. Computational Models to Improve the Stratification of Patients with Spine Metastases\" \/>\n<meta property=\"og:description\" content=\"E. Dall\u2019Ara - University of Sheffield, Insigneo Institute\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/\" \/>\n<meta property=\"og:site_name\" content=\"Centre for Computational Personalized Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/sano.science\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-26T18:54:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@sanoscience\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/\",\"name\":\"147. Computational Models to Improve the Stratification of Patients with Spine Metastases - Centre for Computational Personalized Medicine\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/Sano_Seminar_Dalla_Ara-1024x536.jpg\",\"datePublished\":\"2024-10-11T17:05:20+00:00\",\"dateModified\":\"2025-02-26T18:54:03+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/#primaryimage\",\"url\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/Sano_Seminar_Dalla_Ara.jpg\",\"contentUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/Sano_Seminar_Dalla_Ara.jpg\",\"width\":1200,\"height\":628},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sano.science\\\/seminars\\\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/sano.science\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Seminars\",\"item\":\"https:\\\/\\\/sano.science\\\/seminars\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"147. Computational Models to Improve the Stratification of Patients with Spine Metastases\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sano.science\\\/#website\",\"url\":\"https:\\\/\\\/sano.science\\\/\",\"name\":\"Centre for Computational Personalized Medicine\",\"description\":\"Sano \u2013 Centre for Computational Medicine\",\"publisher\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sano.science\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/sano.science\\\/#organization\",\"name\":\"Sano \u2013 Centre for Computational Medicine\",\"alternateName\":\"Sano\",\"url\":\"https:\\\/\\\/sano.science\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/05\\\/logo_sano_podstawowe.png\",\"contentUrl\":\"https:\\\/\\\/sano.science\\\/wp-content\\\/uploads\\\/2024\\\/05\\\/logo_sano_podstawowe.png\",\"width\":700,\"height\":265,\"caption\":\"Sano \u2013 Centre for Computational Medicine\"},\"image\":{\"@id\":\"https:\\\/\\\/sano.science\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/sano.science\\\/\",\"https:\\\/\\\/x.com\\\/sanoscience\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/sanoscience\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCDZ_8TcjMWUG2ZcgKKgfpwQ\",\"https:\\\/\\\/bsky.app\\\/profile\\\/sanoscience.bsky.social\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"147. Computational Models to Improve the Stratification of Patients with Spine Metastases - Centre for Computational Personalized Medicine","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/","og_locale":"en_US","og_type":"article","og_title":"147. Computational Models to Improve the Stratification of Patients with Spine Metastases","og_description":"E. Dall\u2019Ara - University of Sheffield, Insigneo Institute","og_url":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/","og_site_name":"Centre for Computational Personalized Medicine","article_publisher":"https:\/\/www.facebook.com\/sano.science\/","article_modified_time":"2025-02-26T18:54:03+00:00","og_image":[{"width":1200,"height":628,"url":"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_site":"@sanoscience","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/","url":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/","name":"147. Computational Models to Improve the Stratification of Patients with Spine Metastases - Centre for Computational Personalized Medicine","isPartOf":{"@id":"https:\/\/sano.science\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/#primaryimage"},"image":{"@id":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/#primaryimage"},"thumbnailUrl":"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara-1024x536.jpg","datePublished":"2024-10-11T17:05:20+00:00","dateModified":"2025-02-26T18:54:03+00:00","breadcrumb":{"@id":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/#primaryimage","url":"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara.jpg","contentUrl":"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara.jpg","width":1200,"height":628},{"@type":"BreadcrumbList","@id":"https:\/\/sano.science\/seminars\/computational-models-to-improve-the-stratification-of-patients-with-spine-metastases\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sano.science\/"},{"@type":"ListItem","position":2,"name":"Seminars","item":"https:\/\/sano.science\/seminars\/"},{"@type":"ListItem","position":3,"name":"147. Computational Models to Improve the Stratification of Patients with Spine Metastases"}]},{"@type":"WebSite","@id":"https:\/\/sano.science\/#website","url":"https:\/\/sano.science\/","name":"Centre for Computational Personalized Medicine","description":"Sano \u2013 Centre for Computational Medicine","publisher":{"@id":"https:\/\/sano.science\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sano.science\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/sano.science\/#organization","name":"Sano \u2013 Centre for Computational Medicine","alternateName":"Sano","url":"https:\/\/sano.science\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sano.science\/#\/schema\/logo\/image\/","url":"https:\/\/sano.science\/wp-content\/uploads\/2024\/05\/logo_sano_podstawowe.png","contentUrl":"https:\/\/sano.science\/wp-content\/uploads\/2024\/05\/logo_sano_podstawowe.png","width":700,"height":265,"caption":"Sano \u2013 Centre for Computational Medicine"},"image":{"@id":"https:\/\/sano.science\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/sano.science\/","https:\/\/x.com\/sanoscience","https:\/\/www.linkedin.com\/company\/sanoscience\/","https:\/\/www.youtube.com\/channel\/UCDZ_8TcjMWUG2ZcgKKgfpwQ","https:\/\/bsky.app\/profile\/sanoscience.bsky.social"]}]}},"acf":[],"gutenberg_blocks":[{"blockName":"custom-styles","attrs":{"styles":""}},{"blockName":"core\/heading","attrs":{"epAnimationGeneratedClass":"edplus_anim-yFJAtN","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-abstract\">Abstract:<\/h2>\n","innerContent":["\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-abstract\">Abstract:<\/h2>\n"]},{"blockName":"core\/spacer","attrs":{"height":"20px","epAnimationGeneratedClass":"edplus_anim-lNFnlX","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-trQIa0","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">The spine is the most common anatomical site for the localization of bone metastases from different types of primary tumours (30-70% of patients with cancer, estimated to be ~2.7M in Europe). Fractures occur in 30% of metastatic spines. Currently scoring systems such as the Spine Instability Neoplastic Score (SINS) are used by clinicians to estimate the risk of fracture in these patients and decide who needs treatment, usually an invasive surgery. Nevertheless, these scores are not specific and sensitive enough. CT-based Subject Specific Finite Element (SSFE) models have been used to evaluate the effect of skeletal diseases and related treatments in the spine.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">The spine is the most common anatomical site for the localization of bone metastases from different types of primary tumours (30-70% of patients with cancer, estimated to be ~2.7M in Europe). Fractures occur in 30% of metastatic spines. Currently scoring systems such as the Spine Instability Neoplastic Score (SINS) are used by clinicians to estimate the risk of fracture in these patients and decide who needs treatment, usually an invasive surgery. Nevertheless, these scores are not specific and sensitive enough. CT-based Subject Specific Finite Element (SSFE) models have been used to evaluate the effect of skeletal diseases and related treatments in the spine.<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-7ha4Vl","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">In this seminar I will:<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">In this seminar I will:<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-uNnnFZ","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">-) introduce a new experimental and imaging pipeline to characterize the failure modes of vertebrae with metastatic lesions;<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">-) introduce a new experimental and imaging pipeline to characterize the failure modes of vertebrae with metastatic lesions;<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-5CWzGT","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">-) present a pipeline to create SSFE models of vertebrae with metastatic lesions and adjacent radiographically healthy control vertebrae from CT images of patients with spine metastases;<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">-) present a pipeline to create SSFE models of vertebrae with metastatic lesions and adjacent radiographically healthy control vertebrae from CT images of patients with spine metastases;<\/p>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-cKWROb","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">-) introduce the METASTRA project (<a href=\"https:\/\/www.metastraproject.eu\/\">https:\/\/www.metastraproject.eu\/<\/a>), which is funded by the EU and aims at developing the first decision support tool based on computational models to stratify patients with spine metastases that are at high risk of fracture.<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">-) introduce the METASTRA project (<a href=\"https:\/\/www.metastraproject.eu\/\">https:\/\/www.metastraproject.eu\/<\/a>), which is funded by the EU and aims at developing the first decision support tool based on computational models to stratify patients with spine metastases that are at high risk of fracture.<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"50px","epAnimationGeneratedClass":"edplus_anim-lNFnlX","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/heading","attrs":{"epAnimationGeneratedClass":"edplus_anim-BoA5VB","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-about-the-author\">About the author:<\/h2>\n","innerContent":["\n<h2 class=\"wp-block-heading eplus-wrapper\" id=\"h-about-the-author\">About the author:<\/h2>\n"]},{"blockName":"core\/spacer","attrs":{"height":"20px","epAnimationGeneratedClass":"edplus_anim-lNFnlX","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-FedT8M","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\">Prof. Dall\u2019Ara (<a href=\"https:\/\/www.sheffield.ac.uk\/smph\/people\/clinical-medicine\/enrico-dallara\">https:\/\/www.sheffield.ac.uk\/smph\/people\/clinical-medicine\/enrico-dallara<\/a>) is Professor of Musculoskeletal Biomechanics at the University of Sheffield. He is the Director of the Skelet.Al laboratories, the Research Director of the Insigneo Computational Modelling in Medicine research theme, and the President of the European Society of Biomechanics. His research focuses on better understanding the properties of musculoskeletal tissues across the space and time scales, by using imaging, experimental and computational methods. He has received funding from EPSRC, NC3Rs, BBSRC, FNRS\/FWO, and the European Commission including the recent METASTRA project. In 2024 he has been selected for an ERC consolidator award that has been funded by the EPSRC through the EU Guarantee fund with the title: Virtual Mouse and Human Twins for optimising Treatments for Osteoporosis (VMHTsOP).<\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\">Prof. Dall\u2019Ara (<a href=\"https:\/\/www.sheffield.ac.uk\/smph\/people\/clinical-medicine\/enrico-dallara\">https:\/\/www.sheffield.ac.uk\/smph\/people\/clinical-medicine\/enrico-dallara<\/a>) is Professor of Musculoskeletal Biomechanics at the University of Sheffield. He is the Director of the Skelet.Al laboratories, the Research Director of the Insigneo Computational Modelling in Medicine research theme, and the President of the European Society of Biomechanics. His research focuses on better understanding the properties of musculoskeletal tissues across the space and time scales, by using imaging, experimental and computational methods. He has received funding from EPSRC, NC3Rs, BBSRC, FNRS\/FWO, and the European Commission including the recent METASTRA project. In 2024 he has been selected for an ERC consolidator award that has been funded by the EPSRC through the EU Guarantee fund with the title: Virtual Mouse and Human Twins for optimising Treatments for Osteoporosis (VMHTsOP).<\/p>\n"]},{"blockName":"core\/spacer","attrs":{"height":"50px","epAnimationGeneratedClass":"edplus_anim-lNFnlX","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/image","attrs":{"id":21640,"sizeSlug":"large","linkDestination":"none","epAnimationGeneratedClass":"edplus_anim-8aKR5K","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara-1024x536.jpg\" alt=\"\" class=\"wp-image-21640\"\/><\/figure>\n","innerContent":["\n<figure class=\"wp-block-image size-large eplus-wrapper\"><img src=\"https:\/\/sano.science\/wp-content\/uploads\/2024\/10\/Sano_Seminar_Dalla_Ara-1024x536.jpg\" alt=\"\" class=\"wp-image-21640\"\/><\/figure>\n"]},{"blockName":"core\/spacer","attrs":{"height":"50px","epAnimationGeneratedClass":"edplus_anim-lNFnlX","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n","innerContent":["\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer eplus-wrapper\"><\/div>\n"]},{"blockName":"core\/paragraph","attrs":{"epAnimationGeneratedClass":"edplus_anim-U1Ydoz","epGeneratedClass":"eplus-wrapper"},"innerBlocks":[],"innerHTML":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/terms-and-conditions-of-participation-in-sano-seminars\/\" target=\"_blank\" rel=\"noreferrer noopener\">regulations<\/a><\/p>\n","innerContent":["\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/sano.science\/terms-and-conditions-of-participation-in-sano-seminars\/\" target=\"_blank\" rel=\"noreferrer noopener\">regulations<\/a><\/p>\n"]}],"meta_data":{"event_day":"2024-11-18","event_time":"2:00-3:30 PM (CET)","event_guest":"","has_medias":true,"medias":[{"icon":{"ID":1144,"id":1144,"title":"clock","filename":"clock.svg","filesize":1479,"url":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","link":"https:\/\/sano.science\/seminars\/79-digital-behaviour-change-interventions-dbci-from-design-to-implementation\/clock\/","alt":"clock Sano Seminar","author":"7","description":"","caption":"Sano Seminar clock","name":"clock","status":"inherit","uploaded_to":13471,"date":"2023-06-01 13:24:42","modified":"2024-10-09 16:41:04","menu_order":0,"mime_type":"image\/svg+xml","type":"image","subtype":"svg+xml","icon":"https:\/\/sano.science\/wp-includes\/images\/media\/default.png","width":56,"height":57,"sizes":{"thumbnail":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","thumbnail-width":147,"thumbnail-height":150,"medium":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","medium-width":294,"medium-height":300,"medium_large":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","medium_large-width":768,"medium_large-height":783,"large":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","large-width":1004,"large-height":1024,"1536x1536":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","1536x1536-width":56,"1536x1536-height":57,"2048x2048":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/clock.svg","2048x2048-width":56,"2048x2048-height":57}},"title":"18th November 2024, 2:00-3:30 PM (CET)","link":""},{"icon":{"ID":1146,"id":1146,"title":"camera","filename":"camera.svg","filesize":1129,"url":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","link":"https:\/\/sano.science\/seminars\/79-digital-behaviour-change-interventions-dbci-from-design-to-implementation\/camera\/","alt":"camera Sano Seminar","author":"7","description":"","caption":"Sano Seminar camera","name":"camera","status":"inherit","uploaded_to":13471,"date":"2023-06-01 13:25:24","modified":"2024-10-09 16:42:29","menu_order":0,"mime_type":"image\/svg+xml","type":"image","subtype":"svg+xml","icon":"https:\/\/sano.science\/wp-includes\/images\/media\/default.png","width":60,"height":38,"sizes":{"thumbnail":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","thumbnail-width":150,"thumbnail-height":95,"medium":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","medium-width":300,"medium-height":190,"medium_large":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","medium_large-width":768,"medium_large-height":486,"large":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","large-width":1024,"large-height":648,"1536x1536":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","1536x1536-width":60,"1536x1536-height":38,"2048x2048":"https:\/\/sano.science\/wp-content\/uploads\/2023\/06\/camera.svg","2048x2048-width":60,"2048x2048-height":38}},"title":"Join via ZOOM on","link":{"title":"seminar.sano.science","url":"https:\/\/us06web.zoom.us\/j\/81263292238#success","target":"_blank"}}]},"_links":{"self":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/seminars\/19296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/seminars"}],"about":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/types\/seminars"}],"version-history":[{"count":16,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/seminars\/19296\/revisions"}],"predecessor-version":[{"id":21641,"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/seminars\/19296\/revisions\/21641"}],"wp:attachment":[{"href":"https:\/\/sano.science\/index.php\/wp-json\/wp\/v2\/media?parent=19296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}