New book on protein folding and environmental factors

Edited by Prof. Irena Roterman-Konieczna

We are pleased to share the publication of a new book edited by Prof. Irena Roterman-Konieczna, a member of the International Scientific Committee at Sano.
“Simulating Protein Folding in Variable Environmental Conditions” (Elsevier, 2026) explores how environmental factors—including aqueous and membrane conditions such as pH and temperature—influence protein folding and the mechanisms leading to amyloid formation. The book applies the Fuzzy Oil Drop (FOD-M) model to simulate amyloid transformation in silico and to analyze how external factors drive structural rearrangements in proteins.

Understanding protein misfolding in context

A key strength of the publication lies in its focus on how changes in the external environment affect protein structure and stability. By examining different types of amyloids the authors highlight the role of environmental forces in protein transformation processes. This approach provides valuable insights into the mechanisms of misfolding and aggregation.

The book serves as a useful resource for researchers working in molecular biology, structural biology, biochemistry, computational biology, and related fields, offering both theoretical perspective and practical modeling approaches.