Venous modelling to inform treatment of patients presenting with lower limb thrombosis

Venous modelling to inform treatment of patients presenting with lower limb thrombosis

Sano PhD students Project title: Venous modelling to inform treatment of patients presenting with lower limb thrombosis

  • About us:

Sano Centre for Computational Medicine is a new International Scientific Foundation located in Kraków, Poland.

Sano aspires to be a major translational scientific institute, operating at the meeting point of academic science, established MedTech industry, and emerging start-up environment, combining the best of these three perspectives.

Established with support from the European Commission and the Foundation for Polish Science, Sano aims to be a major driving force behind the advancement of computational medicine for the benefit of healthcare systems worldwide.

Sano acts as a core technology and expertise provider for industry, and creator of innovation, developing state-of-the-art solutions for healthcare. Thanks to the substantial funding and excellent European partnership network, Sano will bring a critical mass to this transformational field of research, in order to translate scientific advancements onto clinical practice. Sano’s ambition is to become the Reference Centre for Computational Medicine in Central Europe and build a reputation as a leading center on a global level.

As a cross-disciplinary institution, Sano uses machine learning/artificial intelligence (ML/AI), large scale computer simulations, data science, and other computational technologies towards overcoming global challenges in healthcare systems. The research agenda will be executed in close collaboration with Partners in Poland, EU and USA.

We value:

  • Passion – Passion in what we do, engagement in Sano operations, taking responsibility, providing initiative, being happy at work.
  • Innovation – Boldness in articulating and pursuing novel ideas, courage to think outside the box.
  • Integrity – Directness, openness, tolerance and respect. Scientific integrity (we do not cut corners).
  • Diversity – Diversity in backgrounds, cultures and opinions of Sano employees. Promotion of women in STEM.
  • About job:
  • Closing date: 18.06.2021
  • Level of education: Master’s degree
  • Hours: 40 hours per week
  • Salary indication: up to 8000 PLN gross monthly


University of Sheffield: Dr. Andrew Narracott (1st supervisor), Prof. Ian Halliday (2nd supervisor) 

Sano: Dr. Zbigniew Struzik (Modeling and Simulation Research Group Leader) 

Project start: July 2021 

Degree Awarding Institution: University of Sheffield 

This project will develop tools designed to be integrated within the current clinical workflow for assessment of patients presenting with deep vein thrombosis in the lower limb, with focus on the ilio-femoral region.  The use of minimally invasive techniques to treat this patient cohort has increased in recent years, but there are significant gaps in the evidence-base to support clinical decision making.  Application of computational techniques to provide enhanced assessment of the haemodynamics in these patients from data currently captured routinely during clinical assessments has the potential significantly to enhance this evidence-base, reducing the cost of patient care and improving quality of life in this cohort.  

The computational tools developed in the project will consider both the relative influence of local venous anatomy in the region of thrombosis and the anatomy and function of the larger-scale venous circulation which determines the boundary conditions on this local region.  Assessment of the uncertainty on model outcomes, due to variability in the clinically measured data will be considered and appropriate mechanisms to present results to clinical end-users will be developed through collaboration with the clinical advisory team. 

  • What are you going to do?

You are expected to: 

  • do original research in this field under the direction of the supervisor; 
  • participate in the many seminars by internal and external speakers as well as journal clubs and group activities; 
  • collaborate with other PhD candidates, postdoctoral researchers and other Sano employees. 
  • What do we require ?

Required background and skills of the candidate: 

  • Ideally a candidate should possess a 1st Class undergraduate Honours degree in a relevant discipline or a Master’s degree (completed or near completion) in a relevant discipline, such as computer science, engineering, physics, etc.; 
  • Practice and theory of Computational Fluid Dynamics, numerical methods, programming skills (e.g. python, Matlab or similar); 
  • an interest in pursuing applied research;  
  • excellent written and oral English communication skills, to meet the entry requirements for PhD study at of the University of Sheffield (IELTS certificate or equivalent) 
  • Our Offer

We offer a fixed term contract for 40 hours per week for the duration of 4 years. This will be supported by an educational plan that includes attendance of courses and (international) meetings. The contract will include opportunities to participate in teaching and supervision of undergraduate and master students.  

The salary, depending on relevant experience before the beginning of the employment contract, will be up to 8000 PLN gross per month, based on a full-time contract (40 hours a week) for the duration of 4 years with private medical care and a sports card. 

This PhD will be a collaboration between Sano and the University of Sheffield. The University of Sheffield will be the degree awarding body. The student will be based in Poland, Krakow operating in conjunction with the Cyfronet supercomputing centre hosted by AGH. Visits to Sheffield will form part of the PhD for purposes of strengthened supervision and training – the student is expected to spend approximately 6 undertaking visits to collaborating institutions including Sheffield during the contract. 

Sano offers excellent opportunities for study and development, an access to many international conferences on computational medicine and a possibility to grow in a scientific society. 

If you feel that this job opportunity is the career that you are looking for, please apply immediately and give Sano a chance to meet you. Please, be informed that Sano will contact only with Candidates fulfilling the formal criteria.

  • Job application

Sano is an equal-opportunity employer. We prioritize diversity and are committed to creating an inclusive environment for everyone. We value a spirit of enquiry and perseverance, provide the space to keep asking questions, and promote a culture of curiosity and creativity.

Do you recognize yourself in the job profile? Then we look forward to receiving your application.

Applications in .pdf should include:

  • a cover letter; 
  • a curriculum vitae; 

During later stages, you’ll also be asked to provide: 

  • copies of your degree certificates; 
  • copies of your English certificates; 
  • two reference letters (to be submitted online by the reference writers).

Apply for a job

Apply through Sano recruitment system. If you would like to apply for future openings feel free to send your application to our database.​